Anti-Helicobacter pylori quadruple

In medicine, the most advanced treatment for Helicobacter pylori is the quadruple therapy, which is developed based on the dual and triple therapy. It mainly inhibits the growth of Helicobacter pylori and eliminates Helicobacter pylori by protecting the gastric mucosa and using antibiotics. The following is a detailed introduction to the principles of the anti-Helicobacter pylori quadruple therapy.

People with peptic ulcer disease are familiar with Helicobacter pylori, and they also know that this small bacteria is associated with gastritis and can even be the cause of gastric cancer. But what exactly is Helicobacter pylori? As long as Helicobacter pylori is detected, does it need to be eliminated immediately? Not at all! Let the experts tell us in which situations Helicobacter pylori eradication is necessary and how to use medication!

In 1982, two Australian scholars, Marshall and Warren, discovered that Helicobacter pylori is a microaerophilic bacterium that colonizes the surface of the gastric mucosal epithelium, and proved that it is related to the onset of chronic gastritis and peptic ulcer, for which they won the 2005 Nobel Prize in Physiology or Medicine.

Don’t be afraid of bacteria

Once infected with Helicobacter pylori, the body is unable to clear the infection on its own, often resulting in lifelong infection.

Helicobacter pylori can colonize and survive in the acidic environment of the gastric cavity through its unique spiral flagella and the urease it produces, producing a variety of toxins that destroy the gastroduodenal mucosal barrier, causing inflammation and immune responses in the body, and ultimately leading to the formation of a series of diseases.

Although Helicobacter pylori infection is quite common among the population, most infected people are asymptomatic throughout their lives. Only a small number of people develop chronic gastritis and peptic ulcers, and a very small number develop into gastric cancer or gastric mucosa-associated lymphoid tissue lymphoma. Therefore, from this point of view, there is no need to be afraid of the bacteria.

Prevent bacteria from entering the body through the mouth

Why do we get infected with Helicobacter pylori and how to prevent it?

Many people mistakenly believe that infection with Helicobacter pylori is an "infectious disease", but in fact it is just a state of infection. Most cases do not cause disease, so it does not fall into the category of infectious diseases, but correcting unhealthy lifestyles is necessary.

Transmission method: Helicobacter pylori generally enters the human body through the mouth and can be transmitted through hands, unclean food, unclean tableware, feces, etc.

Precautions:

1. Asians are accustomed to using chopsticks to eat food from the same tableware, which gives the bacteria in the saliva a chance to spread through the chopsticks, so it is recommended to choose the separate dining system or use serving chopsticks.

2. In my country, many infants are infected with Helicobacter pylori, which is related to mouth-to-mouth feeding of infants by the large population. Therefore, parents who are infected with Helicobacter pylori must pay attention.

3. Studies have also found that Helicobacter pylori can survive in tap water for 4 to 10 days. Therefore, try to drink boiled water and eat cooked food.

4. Toothbrushes and other cleaning supplies should be placed in a ventilated place. The bathroom also needs to be ventilated frequently and exposed to sunlight. Families with conditions can use ultraviolet lamps, which can generally achieve the purpose of sterilization and disinfection in half an hour.

5. Develop good hygiene habits, wash your hands before and after meals, and strictly disinfect commonly used tableware.

Just breathe out and you will know whether there are bacteria or not

Clinical methods for detecting Helicobacter pylori infection are mainly divided into invasive and non-invasive methods.

Invasive methods require endoscopic biopsy first, including rapid urease test, direct smear microscopy of gastric mucosa, microscopy of gastric mucosal tissue sections, bacterial culture, and genetic testing.

Non-invasive methods do not rely on gastroscopy and include carbon 13 or carbon 14 urea breath test, fecal Helicobacter pylori antigen test and serum Helicobacter pylori antibody test.

The urea breath test is currently the most commonly used test in various hospitals. This test method is highly accurate, simple and convenient.

Treatment is not a one-size-fits-all approach

What should I do if Helicobacter pylori infection is detected?

There is a misunderstanding here. Many people believe that Helicobacter pylori infection must be eradicated once it is discovered. However, more than half of the world's population is infected with Helicobacter pylori, and only a small part of them eventually develop related gastrointestinal diseases. In addition, considering the adverse reactions of drug treatment and the bacterial resistance that may be caused by the abuse of antibiotics, not all patients infected with Helicobacter pylori need to be treated.