What does Big and Small Sanyang mean

Many people don’t understand what big triple positive and small triple positive are. In fact, big three positive means that in the two-pair-half test of hepatitis B, the surface antigen, e antigen and core antibody are all positive. The "small three positive" refers to the immunological indicators of chronic hepatitis B patients or hepatitis B virus carriers, in which the hepatitis B surface antigen, e antibody, and hepatitis B core antibody are positive. The difference between the two is that the e antigen is positive and the e antibody is negative in the big triple positive, while the e antigen is negative and the e antibody is positive in the small triple positive.

Long-term untreated hepatitis B virus may cause great harm

The big three positives are highly contagious, contain a large number of hepatitis B viruses, and have a high level of viral replication. When the hepatitis B virus in the body continues to replicate and attack liver cells, the body's own immune system will kill these viruses, but will also deal with normal liver cells, causing liver cell necrosis and lesions, resulting in liver damage and abnormal liver function, further accelerating the progression of the disease.

Clinical manifestations of small triple positive

1. Chronic HBV carriers are mostly asymptomatic and are often in the immune tolerance period. Except for the "big three positives" and positive virus tests, other growth indicators and even pathological indicators are normal. Although no drug treatment is required during this period, regular testing and observation are required to detect disease progression in time. Research on carriers has also shown that a small number of carriers have normal liver function, but the disease still progresses. After several years, it can also progress to hepatitis, cirrhosis and even liver cancer. Therefore, regular check-ups are required to detect disease progression in time and intervene in time.

2. Chronic hepatitis B : It can be divided into three types: mild, moderate and severe according to the condition.

Mild: The condition is relatively mild, with recurrent symptoms of fatigue, dizziness, loss of appetite, aversion to oil, yellow urine, discomfort in the liver area, poor sleep, slightly enlarged liver with slight tenderness, and mild splenomegaly. Some cases have no symptoms or signs. Only 1 or 2 liver function indicators were slightly abnormal.

Moderate: Symptoms, signs, and laboratory tests are between mild and severe.

Severe: There are obvious or persistent symptoms of hepatitis, such as fatigue, poor appetite, abdominal distension, yellow urine, loose stools, etc., accompanied by liver disease face, liver palms, spider nevi, splenomegaly, repeated or persistent increase in ALT and/or aspartate aminotransferase (AST), decreased albumin, and significantly increased immunoglobulin G.