What are the side effects of topical gentamicin

Gentamicin is a broad-spectrum antibiotic that is often used in clinical practice. It has a relatively obvious inhibitory effect on many bacteria such as Klebsiella pneumoniae and Escherichia coli, so it is also widely used. However, it should be noted that since gentamicin is a drug, it may have certain side effects. You should understand it before using it. So, what are the side effects of external use of gentamicin?

Gentamicin tablets side effects

(1) This product is ototoxic and can cause irreversible damage to hearing, (cochlear) and balance (vestibular) functions, resulting in hearing loss, tinnitus or aural fullness, dizziness, unsteady gait, etc. Children, the elderly, long-term drug users, and patients with impaired renal function must undergo drug concentration monitoring and hearing or vestibular function monitoring. Use with caution in pregnant women.

(2) This product may occasionally cause renal damage such as increased urination and decreased urination, but most of these damages are reversible. Patients must ensure adequate water intake to reduce renal tubular damage. Patients with renal dysfunction should use this product with caution.

(3) This product can cause neuromuscular blockade and neurotoxic reactions, resulting in weakness, numbness, tingling, burning sensation in the face, cranial nerve damage, myasthenia gravis, and paralysis agitans.

Large doses of medication can easily lead to edema

Large doses may cause urinary retention, acute renal failure, and neurological symptoms. Inhalation may cause allergic reactions and asthma. Eye drops may cause edema and toxic conjunctivitis. This product may occasionally cause respiratory depression, which has been reported both at home and abroad. This product may also occasionally cause polyneuropathy and toxic encephalopathy. Allergic reactions are rare, and skin itching, urticaria, etc. may occasionally occur, which generally do not affect the continued use of the drug, and the rash will quickly subside after stopping the drug. Occasionally, this product may cause allergic leukopenia and neutropenia. This product may occasionally cause anemia, leukopenia, granulocytopenia, thrombocytopenia, and hypotension. This product can cause gastrointestinal discomfort symptoms such as nausea, loss of appetite, vomiting, and abdominal distension. A small number of patients may experience changes in liver function, such as increased serum aminotransferase and positive flocculation reaction. Dual infection also occurs.