What are the characteristics of comprehensive interventional treatment for liver cancer? Comprehensive analysis of comprehensive interventional treatment methods for liver cancer

Methods such as TACE and non-vascular intervention have their shortcomings, and the comprehensive application of different methods lacks complementarity. There are many combined methods to improve the efficacy, and good results have been achieved.

Currently, the common comprehensive application methods include: double chemoembolization, TACE combined with ablation, TACE combined with gene therapy, etc.

1. Liver cancer is mainly supplied by the hepatic artery, but most of them have the characteristics of dual blood supply. Some people have tried to use dual intervention of the hepatic artery and portal vein to treat liver cancer, but this technology has been developed for a short time and needs further research.

2. The combined application of TACE and local ablation therapy is widely used in clinical practice, effectively avoiding the shortcomings of each, and achieving good results. In some cases, combined application can achieve cure. For lesions smaller than 3 cm, it can also completely necrotize the tumor and achieve the purpose of radical cure.

3. After the recombinant human p53 gene adenovirus injection enters clinical application, the use of interventional methods and transarterial administration can increase the concentration of the target gene in the target organ, relatively directional expression, increase the transfection rate, and reduce systemic adverse reactions. Mixing with iodized oil for hepatic artery embolization allows it to be slowly released locally in the tumor to improve transfection efficiency. Clinical studies have shown that it has a good therapeutic effect, but further research is needed. The combined use of TACE and gene therapy is one of the trends in interventional treatment of liver cancer, which can enhance the efficacy.