Ion disorder can cause people to have many medical reactions. Severe patients may even directly affect their normal work. However, most patients will only feel that they have no strength in their bodies, often feel weak, and have no interest in their studies. They will gradually feel that their emotions have become particularly irritable and restless. Therefore, they must find out the cause of their illness so that they can alleviate their clinical symptoms. Clinical manifestations 1. Hypernatremia The clinical manifestations are atypical and fatigue may occur. Dry lips and tongue, loss of skin elasticity, irritability, and even mania, hallucinations, delirium and coma. Brain atrophy caused by hypernatremia may be followed by cerebral hemorrhage, subarachnoid hemorrhage, and even death. 2. Hyponatremia Mild hyponatremia (serum sodium concentration 120-135mmol/L) may cause loss of taste and muscle aches; moderate hyponatremia (serum sodium concentration 115-120mmol/L) may cause headache, personality changes, nausea, vomiting, etc.; severe hyponatremia (serum sodium concentration <115mmol/L) may cause coma and loss of reflexes. 3. Hyperkalemia It manifests in three aspects: ① Severe physical symptoms such as bradycardia, atrioventricular block and even sinus arrest. The electrocardiogram shows tall and sharp T waves. In severe cases, the PR interval is prolonged, the P wave disappears, the QRS wave widens, and eventually the heart stops beating. In the early stage, the blood pressure increases slightly, and in the later stage, the blood pressure decreases, and there are irregular breathing and arrhythmias. ② Neuromuscular symptoms manifest in the early stages as muscle pain and weakness, and when the symptoms are most severe in the extremities, respiratory muscle paralysis may occur. ③ Early manifestations of mental symptoms include apathy, slow response to the outside world, excitement, emotional instability, restlessness, etc. In severe cases, there will be impaired consciousness, drowsiness, coma, etc. 4. Hypokalemia It is not only related to the concentration of serum potassium, but also closely related to the speed of hypokalemia. Therefore, in patients with slow onset, although hypokalemia is severe, the clinical symptoms may not be obvious. On the contrary, in patients with acute onset, although hypokalemia is not severe, the clinical symptoms may be very significant: ① Physical symptoms include lack of appetite, abdominal distension, thirst, nausea, vomiting, chest tightness, palpitations, and severe myocardial involvement, which can lead to heart failure. The initial electrocardiogram shows flat or absent T waves and the appearance of U waves. In severe cases, ventricular tachycardia, ventricular fibrillation or sudden death may occur. ② Neuromuscular symptoms are the most prominent symptoms of hypokalemia, and the important manifestations are decreased muscle strength and weakness in the limbs, flaccid paralysis and periodic paralysis. ③ Early manifestations of mental symptoms include fatigue, emotional indifference, memory loss, depression, and stupor. In severe cases, there may be impaired consciousness, drowsiness, delirium and even coma. 5. Hypercalcemia Slow reaction, indifference to the outside world, emotional apathy and memory impairment; may also have hallucinations, delusions, depression and other symptoms; severe cases may have drowsiness, coma and other consciousness disorders 6. Hypocalcemia Common neuropsychiatric symptoms include hand and foot convulsions, epileptic seizures, paresthesias, increased muscle tension, hyperreflexia of tendons, muscle tenderness, impaired consciousness, etc. Bronchospasm, laryngeal spasm and respiratory failure may also occur. |
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