What is the reason for high creatinine

Clinically, muscle metabolism in people's bodies is called creatinine. Many people don't know much about creatinine, but when the creatinine component in serum is abnormal, it is often a sign of disease. Many clinical disease examinations also require creatinine testing, and the clinical significance of creatinine is also very broad. Generally, when patients with kidney disease go to the hospital for examination, creatinine will also be checked. This shows that creatinine is also related to kidney disease. When testing creatinine, there are specific values ​​to determine whether it is normal. When creatinine is too high, it will definitely have an impact on the body. The reasons why creatinine is higher than normal are relatively complicated. In addition to being related to disease, lifestyle factors may also play a role.

1. Kidney infection

Patients with renal insufficiency who have infections such as colds and intestinal infections will experience elevated creatinine levels in the short term. In this case, various infections should be treated actively to avoid worsening of the disease.

2. Relapse of kidney disease

Patients with kidney disease, especially those with renal insufficiency, have kidney lesions and severe damage to the glomeruli, which seriously reduces the filtering effect of blood creatinine. As a result, a large amount of blood creatinine cannot be excreted from the body through urine, resulting in high creatinine. If chronic glomerulonephritis, nephrotic syndrome, renal insufficiency, etc. are not treated thoroughly, or if infection occurs in the late stage, it is easy to cause recurrence of the disease and the patient will experience an increase in blood creatinine. In addition, patients may also experience clinical symptoms such as oliguria or even anuria. In this case, various kidney diseases should be actively treated. When the disease is under control, creatinine levels will return to normal levels.

3. Drug poisoning

If patients with kidney disease take drugs that are harmful to the kidneys, their creatinine will increase in a short period of time. If encountering this situation, the patient should stop taking this medication immediately and contact his or her attending physician in time for timely treatment. If the best treatment time is missed, it is likely to cause irreparable damage to the kidneys.

4. Increased blood pressure or blood sugar

For patients with kidney disease, if hypertension occurs, blood pressure should always be controlled, and if diabetes occurs, blood sugar should always be controlled. However, if the blood pressure and blood sugar of kidney patients are not controlled, creatinine will continue to rise.

5. Lifestyle

Overwork, excessive physical exertion, too much sexual intercourse, excessive sweating, reduced water intake, and increased urine output can lead to blood thickening, increased blood concentration, and energy consumption, which can also cause an increase in creatinine in the body.

6. Other diseases

Patients with hypertension, diabetes, etc., who have long-term hypertension and persistent severe proteinuria, and whose condition is not controlled in time, will have high creatinine levels during the course of the illness.