What is the normal level of retinol binding protein?

Retinol binding protein can mainly supplement vitamins for the human body. It is used for vitamin A deficiency, malabsorption syndrome, liver disease, and hyperfunction of small functions that many people have now. It also has a good effect on trauma or infection. It has a good regulating effect on acute and chronic nephritis, diabetic nephropathy, chronic renal failure, and surgical pathology and organ diseases of many people now. The effect brought to our body by insignificant cells can be said to be great, and it also affects the normal value of the human body. Therefore, everyone should have enough understanding and knowledge of this in normal times, and find some cells or values ​​​​of their significance to the body. Only in this way can we ensure the health of the body.

Normal value

Normal value of retinol binding protein:

ELISA method, RIA method:

Male: 36~56mg/L (36.0~56.0μg/ml);

Female: 26.7~57.9mg/L (26.7~57.9μg/ml).

Widely distributed in blood, urine, cerebrospinal fluid and other body fluids.

Linear range: serum: 0.5~140ug/ml

Urine: 0.1~18ug/ml

Reference value: serum: 25~70ug/ml

Urine: <0.7ug/ml

Clinical significance

reduce

Vitamin A deficiency, hypoproteinemia, malabsorption syndrome, liver disease (excluding fatty liver caused by overnutrition), obstructive jaundice, hyperthyroidism, infection, trauma, etc.

Elevated

Renal insufficiency and fatty liver due to overnutrition.

Urine RBP↑: acute and chronic nephritis, diabetic nephropathy; chronic renal failure[1]

Serum RBP↓: acute and chronic hepatitis; liver cirrhosis;

Applicable Departments

1. Nephrology (Nephrology, Renal Surgery)

Used for general screening of kidney disease, acute kidney injury, chronic nephritis, pyelonephritis, glomerular injury, tubular injury, kidney stones, kidney transplant effect evaluation, diabetic nephropathy, hypertensive nephropathy, etc.

2. ICU Department

(1) After surgery: cardiac surgery (after cardiopulmonary bypass), renal surgery (kidney transplantation), cerebral surgery (cerebral hemorrhage and brain trauma), and digestive surgery (liver transplantation);

(2) Nephrotoxic drugs: Thousands of drugs can cause nephritis, such as antibiotics, anti-tumor drugs, cardiovascular drugs, anti-peptic ulcer drugs, diuretics, and some Chinese medicines for antipyretics and analgesia.

(3) Multiple organ failure, cardiopulmonary syndrome, cardiorenal syndrome, hepatorenal syndrome, etc.;

(4) Sudden situations: shock (septic shock, cardiogenic shock), hypovolemia, etc.

3. Emergency Department

Acute trauma patients, cerebral hemorrhage, brain trauma, poisoning (food, poisonous mushrooms, snake bites), infection (hemorrhagic fever, malaria, sepsis, various gastrointestinal infections)

4. Endocrinology

Kidney complications of diabetes

5. Department of Gastroenterology:

Acute liver failure, acute pancreatitis, upper gastrointestinal bleeding;

6. Respiratory Department: Pneumonia

7. Cardiology: heart failure, cardiopulmonary syndrome, ischemic heart failure, acute coronary syndrome

8. Geriatrics:

Screen and promptly detect various renal complications caused by renal damage, renal functional decline and other reasons.

9. Pediatrics:

Children with Henoch-Schonlein purpura, neonatal asphyxia, screening and timely detection of various renal damage and complications;

10. Others

Early stage of pregnancy-induced hypertension, systemic lupus erythematosus, pesticide poisoning, occupational heavy metal poisoning, cancer patients, etc.

People who need to be tested

The degree of renal proximal tubule damage can also be used as an indicator of early liver function damage and monitoring treatment.