What is the reason for high glutamic transaminase

Glutathione aminotransferase is an important indicator of liver examination. When a patient has liver disease, glutathione aminotransferase often increases. In addition, cardiomyopathy, kidney disease, or skeletal muscle can also easily lead to elevated glutathione aminotransferase. Glutathione aminotransferase is a substance in the blood. When glutathione aminotransferase increases, it means that the liver function is seriously damaged, which often leads to chronic liver disease, cirrhosis, and even liver cancer. Patients also often experience insomnia, fatigue, and sallow complexion. People who drink alcohol for a long time or patients with cholecystitis may cause an increase in this indicator.

Causes

1. There are many reasons for high alanine aminotransferase levels. Significant increase is mainly seen in acute viral hepatitis, moderate increase is seen in chronic hepatitis, active cirrhosis, liver cancer, liver abscess, taking medications (especially those that are harmful to the liver), etc.

2. Mild increases can also be seen in myocardial infarction, myocarditis, heart failure; long-term drinking or drinking a large dose at one time, as well as heart failure, fever and other symptoms in certain biliary diseases and heart diseases. In addition, normal pregnancy, preeclampsia, acute fatty liver of pregnancy, etc. are also common causes of elevated transaminase.

Clinical manifestations

1. The clinical manifestations of high alanine aminotransferase include insomnia, fatigue, poor appetite, low fever, aversion to greasy food, jaundice, nausea, vomiting, abdominal pain, diarrhea, and discomfort in the liver area. Mild symptoms include sweating, drowsiness, thirst, and eye fatigue when reading.

2. Damage to the patient's liver, leading to continuous damage to liver cells. At the same time, high alanine aminotransferase levels reduce the liver's metabolic and detoxification abilities, resulting in drug metabolism and body toxins not being excreted in a timely manner, further increasing the burden on the liver.

Treatment principles

1. If the increase of transaminase is caused by physiological factors, you need to stay away from these factors in your life. If the elevation of transaminase is clearly caused by pathological factors, the cause must be identified and symptomatic treatment must be given accordingly.

2. The treatment of high transaminase levels must also follow certain principles. If high transaminase levels are caused by viral hepatitis, antiviral treatment is required while protecting the liver and lowering enzymes.