Depression is a common mental problem. Many people suffer from depression due to excessive stress. The incidence of depression is quite wide. For example, many students will suffer from depression due to excessive study pressure and need to take a leave of absence from school. Of course, it is necessary to take a leave of absence from school to adjust your mental state, and of course certain treatments are also needed to completely cure this disease. 1. Treatment goals The treatment of depressive episodes should achieve three goals: 1. Improve the clinical cure rate and minimize the disability and suicide rates. The key is to completely eliminate clinical symptoms; 2. Improve the quality of life and restore social functions; 3. Prevent relapse. 2. Treatment principles ① Individualized treatment; ② Gradually increase the dose, and use the minimum effective dose as much as possible to minimize adverse reactions and improve medication compliance; ③ Adequate dose and sufficient course of treatment; ④ Use a single medication as much as possible. If the effect is not good, consider switching treatment, enhancing treatment or combined treatment, but pay attention to drug interactions; ⑤ Informed consent before treatment; ⑥ Closely observe changes in the condition and adverse reactions during treatment and deal with them in a timely manner; ⑦ Can be combined with psychological treatment to increase efficacy; ⑧ Actively treat other physical diseases, substance dependence, anxiety disorders, etc. that co-occur with depression. 3. Drug treatment Medication is the main treatment for moderate or severe depressive episodes. Currently, the first-line antidepressants in clinical practice mainly include selective serotonin reuptake inhibitors (SSRI, represented by drugs fluoxetine, paroxetine, sertraline, fluvoxamine, citalopram and escitalopram), serotonin and norepinephrine reuptake inhibitors (SNRI, represented by drugs venlafaxine and duloxetine), norepinephrine and specific serotonergic antidepressants (NaSSA, represented by drug mirtazapine), etc. The use of traditional tricyclic and tetracyclic antidepressants and monoamine oxidase inhibitors has been significantly reduced due to their significant adverse reactions. 4. Psychotherapy For patients with depressive episodes with obvious psychosocial factors, psychotherapy is often required in combination with drug treatment. Commonly used psychotherapy methods include supportive psychotherapy, cognitive behavioral therapy, interpersonal therapy, marital and family therapy, psychodynamic therapy, etc. Among them, the effectiveness of cognitive behavioral therapy for depressive episodes has been recognized. 5. Physical therapy In recent years, a new physical therapy method has emerged - repetitive transcranial magnetic stimulation (rTMS) therapy, which is mainly suitable for mild to moderate depressive episodes. |
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