What to do with myeloma pain, common treatment methods

The early symptoms of myeloma are generally not obvious, so many patients are unaware of it. Only when the disease progresses will symptoms such as bone pain, bleeding, and impaired kidney function appear. Treatment should be taken in a timely manner. Common methods include radiotherapy and chemotherapy.

1. Combination therapy: Increased phosphorylation is one of the mechanisms of tumor cell resistance to chemotherapy drugs, and the calcium channel blocker Verapamil has the effect of reducing phosphorylation. Relevant data show that verapamil can reverse the resistance of patients with refractory multiple myeloma to the VAD regimen.

2. Radiotherapy: Radiotherapy is one of the common methods for treating multiple myeloma, but it is generally used less frequently. Because it has certain limitations. Generally speaking, radiation therapy is only suitable for patients with myeloma, bone pain in part of the body, and symptoms of spinal cord compression.

3. Hematopoietic stem cell transplantation: Hematopoietic stem cell transplantation can also be used to treat multiple myeloma. If the family conditions of the multiple myeloma patient are good, it is recommended that the patient treat multiple myeloma through autologous hematopoietic stem cell transplantation. In addition, for some patients who are relatively young and have serious conditions, they can also make a comprehensive consideration based on their actual situation to decide whether to choose allogeneic hematopoietic stem cell transplantation for treatment.

4. Chemotherapy: Chemotherapy is one of the methods for treating multiple myeloma. If the patient's physical condition is suitable for autologous transplantation. Patients are then advised to choose a combination therapy that does not include melphalan. The drugs commonly used in this combination therapy are mainly the following: Velcade, dexamethasone, thalidomide, lenalidomide, etc. In addition, there is a group of patients whose physical conditions do not allow for autologous transplantation. For patients with this type of multiple myeloma, we can choose another chemotherapy method, which is a combination therapy that includes melphalan. In addition to the commonly used drugs such as Velcade, dexamethasone, thalidomide and lenalidomide, this combined treatment method also requires the use of other drugs such as melphalan.

The above is a detailed introduction to "Several common methods of treating multiple myeloma". I hope it can help the majority of patients and friends. Myeloma patients who are symptomatic or asymptomatic but have developed multiple myeloma-related organ failure should be treated early.