Urine protein is what we commonly call proteinuria. Urine protein 3+ is a severe symptom. The more + signs in urine protein, the more severe the symptoms. Therefore, when you find that you have urine protein, you must seek treatment as soon as possible. However, many people do not know how they got this disease. Next, let’s take a look at what urine protein +3 means. After confirming that it is proteinuria, the first thing to consider is whether it is physiological, that is, caused by factors such as exercise, fever, sympathetic nerve excitement, etc.; if so, this type of proteinuria will often disappear on its own after the inducement is removed. The amount of urine protein is not the only basis for determining whether it is glomerulonephritis, nor is it the only indicator for determining the severity of kidney disease. When a large amount of urine protein appears clinically, it can only be preliminarily diagnosed as glomerular disease. The final diagnosis requires further examination, including renal puncture biopsy. It should be pointed out that the accompanying symptoms of proteinuria are often more important than proteinuria itself. Therefore, after measuring proteinuria, it is necessary to observe whether there is oliguria, hematuria, edema, hypertension, renal function damage, rash, fever, joint pain, anemia, weight loss, or a history of other diseases such as diabetes and hepatitis. This is extremely important for judging the severity of nephritis and whether it is secondary glomerulonephritis. Proteinuria refers to a positive reaction in a routine urine protein qualitative test. The normal glomerular filtration membrane has a selective filtration effect on plasma proteins, which can effectively prevent most plasma proteins from being filtered through the glomerulus, and only a very small amount of plasma proteins enters the glomerular filtrate. Therefore, under normal circumstances, routine urine analysis will be negative for urine protein. When suffering from kidney disease, the permeability of the glomerular filtration membrane increases, and a large amount of protein will be filtered into the glomerular filtrate, far exceeding the reabsorption capacity of the renal tubules. The protein enters the final urine and causes proteinuria. This is more common in primary or secondary glomerular diseases, renal circulation disorders, hypoxia, etc. This type of urine protein can be as small as a few grams per day, and most of the time it is >2 grams/24 hours of urine. Dysfunction of renal tubular reabsorption and reduced reabsorption of protein in the glomerular filtrate can also cause proteinuria, which is common in glomerular interstitial diseases caused by various reasons, such as pyelonephritis, analgesic nephropathy, antibiotic kidney damage, heavy metal poisoning, congenital polycystic kidney and various congenital tubular diseases. The protein content of this type of proteinuria is generally less than 2 grams/24 hours of urine, and most of them are around 1 gram/24 hours of urine. |
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