Is digestive ulcer disease serious?

Gastrointestinal ulcers are actually a serious disease problem, and these diseases pose a threat to the digestive health of many people. Common causes of gastrointestinal ulcers include genetic factors, changes in geographical environment and climate, and poor diet.

1. Heredity: The incidence of gastric ulcers, especially among male relatives, is higher than that of the general population. Sometimes, several generations in a family can be found to have peptic ulcers. Twins living in different places also occasionally suffer from the disease, which suggests that the disease may be related to heredity.

2. Changes in geographical environment and climate seasons: The incidence of this disease has significant geographical differences. For example, in the United States, the United Kingdom and other countries, duodenal ulcers are more common than gastric ulcers, while in Japan, the opposite is true, with the incidence of gastric ulcers being higher than that of duodenal ulcers. Changes in climate and seasons are also significantly correlated with the incidence of gastric ulcers, which tend to occur in late autumn and early spring.

3. Diet: Food can cause physical or chemical damage to the gastric mucosa. According to literature reports, a kind of kimchi in Japan can cause severe antral gastritis and may be a causative factor of gastric ulcer. There is no definitive conclusion as to whether alcohol plays a role in the etiology of this disease, but most people believe that alcoholics are more susceptible to this disease. In addition, malnutrition, overdrinking and overeating can all induce gastric ulcers.

4. Emotions: Continuous and intense mental tension, anxiety, depression and other emotions, long-term excessive mental work, and lack of proper adjustment and rest have a certain impact on the onset and aggravation of gastric ulcers. ?

5. Smoking: It is accepted by most people that smoking is a condition for the formation of gastric ulcers and aggravates existing ulcers.

6. Drugs: Some drugs such as aspirin, indomethacin, phenylbutazone, and glucocorticoids have been listed as ulcer-causing substances. Among them, aspirin is the most important ulcer-causing drug. Many antipyretic, analgesic and cold treatment medicines contain aspirin. Long-term and excessive use can cause gastric ulcers.

7. Patients with certain diseases, such as gastrinoma, primary hyperparathyroidism, emphysema, cirrhosis, renal insufficiency and excessive small bowel resection, are prone to ulcer disease, which has received increasing attention in my country. For example, patients with emphysema may develop gastric ulcers due to the reduced acid resistance of the local mucosa. Gastrinoma is undoubtedly caused by the secretion of a large amount of gastrin to stimulate parietal cells, causing a large amount of gastric acid secretion to damage the gastric mucosa and lead to the formation of gastric ulcers.