Hepatitis B e antibody is positive, it turns out to be like this

I believe that many people are afraid of hepatitis B. Not only is it contagious, but it is also difficult to cure. We know that hepatitis B is a disease, but do you know what the examination indicators for hepatitis B are? Especially hepatitis B E antibody positive, do you know what it means? I believe many people have encountered it. Today we will introduce to you in detail what hepatitis B E antibody positive is and understand its significance.

A positive hepatitis B e antibody actually means that the fourth item in the hepatitis B two-pair-and-a-half test is positive, which indicates that the hepatitis B virus is not actively replicating in the human body and its infectiousness is very low or very little.

If the hepatitis B surface antibody is positive and the e antibody is positive, it means that the hepatitis B virus has been cleared and is in the recovery period of viral infection and antibodies have been produced in the body.

If the hepatitis B surface antibody is positive and the e antibody is positive, it means that the hepatitis B virus has been cleared

Clinical significance

1. It indicates an acute infection. It can be manifested as hepatitis B surface antibody (anti-HBs), hepatitis B core antibody (anti-HBc) and hepatitis B e antibody (anti-HBe) are all positive, which indicates that the hepatitis B virus in the body has been cleared and the condition has improved.

2. Chronic persistent infection with simultaneous presence of surface antigen (HBsAg) and hepatitis B core antibody (anti-HBc) is known as hepatitis B virus (HBV) positive.

3. A small number of people who are positive for hepatitis B e antibody (anti-HBe) and other antibodies are still positive for HBV-DNA.

4. After successful injection of hepatitis B vaccine, only hepatitis B e antibody (anti-HBe) will be positive, and hepatitis B surface antibody (anti-HBs) will not be positive at the same time. This is related to personal constitution.

Negative to positive

There are two very different situations when the hepatitis B E antibody turns from negative to positive

1. In patients whose serum aminotransferase levels remain normal and whose hepatitis B E antibody turns from negative to positive, it indicates that the replication of hepatitis B virus is very low. According to the comparison table of the results of the two-pair-and-a-half hepatitis B examination, HBV-DNA cannot be detected in the serum, and the patient is in the recovery period of infection.

2. Most of those with high or repeatedly fluctuating serum transaminase, HBVDNA-positive hepatitis B E antibody-negative turning positive have chronic hepatitis B, which is due to viral mutation. Patients with high levels of hepatitis B E antibodies need timely treatment. The investigation found that the risk of hepatitis B cancer is on the rise when the hepatitis B E antibody is high, which should attract the attention of patients.