Rectal tubular adenoma with low-grade intraepithelial neoplasia is extremely harmful

With the popularization of colonoscopy among medical students, more and more diseases are exposed to our eyes. Among them is a disease called rectal tubular adenoma with low-grade intraepithelial neoplasia. Many people are frightened by it. What kind of disease is this? Will it lead to cancer? Let us learn about it.

The so-called low-grade intraepithelial neoplasia includes mild dysplasia and moderate dysplasia, which are benign tumors. Don't worry, as long as the removal is complete and there is no residue, there will be no worry about cancer. A follow-up examination should be conducted approximately half a year after the operation, and the intervals for subsequent follow-up examinations can be determined at the discretion of the patient.

In the new classification of colorectal tumors by the World Health Organization, the concept of intraepithelial neoplasia was introduced and regarded as a synonym for dysplasia. Mild and moderate dysplasia are classified as low-grade intraepithelial neoplasia, and severe dysplasia and carcinoma in situ are classified as high-grade intraepithelial neoplasia. Those morphologically indeterminate invasive carcinomas within the lamina propria, but lack evidence of invasion through the muscularis mucosa into the submucosa, are classified as high-grade intraepithelial neoplasia.

Tubular adenoma with low-grade intraepithelial neoplasia is a precancerous lesion and is still a benign tumor. If the tumor area is large (polyp diameter exceeds 5MM), high-frequency electroresection can be performed under colonoscopy. When the polyp diameter is large and ultrasound endoscopy indicates invasion of the submucosal layer, surgical resection is required. Pay attention to monitoring after surgery and check the colonoscopy every 3-6 months. If the tumor area is small (polyp diameter is less than 5MM), no treatment is required, and colonoscopy should be checked every 3-6 months and mucosal biopsy should be taken. If the colonoscopy shows obvious growth and the biopsy indicates high-grade epithelial neoplasia (some people classify tubular adenoma with severe intraepithelial neoplasia as carcinoma in situ), it should be removed. There are two methods of resection, which depend on the size of the lesion and the depth of involvement.

Guidance:

The decision of whether to treat or not and the method of resection will be determined depending on the size of the tumor area. The details are described in the condition analysis.

Life care:

Tubular adenoma with low-grade intraepithelial neoplasia is a precancerous lesion and a benign tumor itself. To prevent canceration, larger lesions are removed and smaller lesions can be observed and followed up.