The diagnostic criteria for systemic vasculitis should be done like this

Systemic vasculitis is an inflammation characterized by vascular necrosis. It is very common in today's medicine, so its early identification and diagnosis are becoming increasingly important. As patients, we should understand the disease. Let us look at the diagnostic criteria for systemic vasculitis.

Most of them are acute, usually with symptoms such as headache, irregular fever, malaise, fatigue, joint and muscle pain. The course of the disease varies and the severity varies. If the patient is exposed to the antigen once, the disease will heal in 3 to 4 weeks. If the patient is exposed to the antigen repeatedly, the disease will recur and the course of the disease may last for months or years. The lesions may invade the mucosa, causing epistaxis and hemoptysis. Kidney involvement causes proteinuria and hematuria, and severe renal failure is the main cause of death. Invasion of the intestines may cause gastrointestinal symptoms such as abdominal pain, steatorrhea, bloody stools, and acute cholecystitis.

Chest X-ray examination showed pneumonia and nodular shadows, pleurisy or pleural effusion. It can invade the nervous system, causing symptoms such as headache, diplopia, delusions, mental confusion, and even cerebral thrombosis and paralysis, dysphagia, sensory and/or motor dysfunction, etc. Cardiac damage includes myocardial infarction, heart rhythm disorders, and pericarditis. Renal cortical ischemia may produce severe hypertension. The most common ocular manifestations of systemic vasculitis are episcleritis and retinal hemorrhage. Painful swelling of the epididymis and testicles may be a manifestation of vasculitis.

Diagnostic criteria:

1) Systemic vasculitis has no specific clinical manifestations. Its manifestations can be seen in diseases such as infection and tumor. However, when it cannot be explained by common diseases, especially when multiple systems are involved and the indicators reflecting the acute phase of inflammation (erythrocyte sedimentation rate, CRP, etc.) are abnormal, the presence of vasculitis should be highly suspected and further corresponding examinations should be performed to confirm the diagnosis. SKLEN clinical manifestations; S stands for skin; K stands for kidneys; L stands for lungs; E stands for ears, nose, and throat; N stands for nerves; if the above three systems are involved, vasculitis should be considered

2) Please note that the current diagnostic criteria for vasculitis are only classification criteria. Please refer to the Chinese Society of Rheumatology's diagnosis and treatment guidelines for details.

3) The diagnosis of systemic vasculitis requires comprehensive judgment based on clinical manifestations, laboratory tests, pathological biopsy data and imaging data including chest X-ray, angiography, CT/MRI, etc. to determine the type of vasculitis and the extent of the lesions.

Vasculitis should be considered if the following cannot be explained:

Multi-system damage; progressive glomerulonephritis or elevated blood Cr and BUN; variable shadows or fixed shadows/cavities in the lungs;

Multiple mononeuritis or polyneuritis; fever of unknown origin; ischemic or congestive symptoms and signs; purpuric rash or livedo reticularis; nodular necrotizing rash; pulselessness or elevated blood pressure; ANCA positive; AECA positive.