As we all know, leukopenia is very harmful to human health, but most people don’t know why leukopenia occurs. In fact, there are many reasons that can cause leukopenia in daily life, and in most cases it is caused by neutropenia. Causes of leukopenia When the white blood cell count in peripheral blood is persistently below 4.0×109/L, it is called leukocytopenia. Since the main components of white blood cells are neutrophils and lymphocytes, especially neutrophils, in most cases, leukopenia is caused by neutrophilia. When the neutrophil count is lower than (1.5-1.8)×109/L, it is called neutropenia. Common causes of low white blood cell count include viral infection, typhoid fever, and medication. The common causes of low white blood cells include viral infection, typhoid fever, etc., and some are caused by drugs. If the granulocytopenia is caused by drugs, the drugs should be stopped immediately and appropriate anti-leukocytogenic drugs should be used, such as colony stimulating factor (CsF), lithium carbonate, madder diepoxide, polyantigen A, etc. Stop exposure to radiation or other chemical toxins. Caused by hypersplenism, prone to recurrent and severe infection, splenectomy may be performed. Its etiology and pathogenesis can be divided into the following three aspects according to cell dynamics ① Leukocyte production disorders, including decreased proliferation or regeneration disorders of stem cells. ② Excessive destruction of white blood cells. Due to infection and immunological factors, excessive destruction of white blood cells leads to a decrease in the number of white blood cells in the peripheral blood. ③ Abnormal granulocyte distribution. Due to various reasons, the number of white blood cells in the marginal pool increases, while the number of white blood cells in the circulating pool decreases, which can also lead to leukocytopenia. Leukocytopenia patients do not have many subjective symptoms, with fatigue and dizziness being the most common. In addition, they may also have loss of appetite, sore limbs, insomnia, low fever, chills, back pain, and palpitations. It is often ignored by doctors and patients and diagnosed as other diseases. At this time, the total white blood cell count must be checked repeatedly. If it remains below 4.0×109/hour, it can be diagnosed as leukocytopenia. Leukopenia In addition to treating the cause, the appropriate treatment plan should be selected according to different patients and the pathogenesis of the disease. Definition of Leukopenia White blood cells are a type of blood cell with a nucleus. The normal blood cell count is 4000-10000/UL (microliter). The number of white blood cells in the blood varies greatly at different times of the day and in different functional states of the body. When the number exceeds 10,000 per microliter, it is called leukocytosis; when it is less than 4,000 per microliter, it is called leukopenia. When the body is inflamed (i.e. inflamed), leukocytosis will occur; leukocytopenia can be hereditary, familial, acquired, etc. The majority of them are acquired. Drugs, radiation, infection, toxins, etc. can all cause granulocytopenia, with drug-induced granulocytosis being the most common. Avoiding medication is to avoid leukopenia caused by the medication. Leukopenia refers to a group of symptoms caused by a sustained decrease in the number of peripheral white blood cells. Typical symptoms include dizziness, fatigue, soreness and weakness of limbs, loss of appetite, mental depression and low fever, which fall into the category of "deficiency and fatigue" in traditional Chinese medicine. Traditional Chinese medicine treats leukocytopenia by invigorating qi and nourishing blood, tonifying the kidney and replenishing essence, and strengthening the spleen and nourishing the stomach. |
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