Causes of high aminotransferase

Everyone wants to maintain the health of their internal organs. So when their aminotransferase levels are high, many patients who are particularly familiar with this disease are worried that it will cause serious damage and destruction to their liver and other organs. So they want to fully understand the reasons for high aminotransferase levels. The answer is given below, you can continue to learn more.

Since transaminases are present in all tissues and organs of the human body, there are many reasons for the increase in serum transaminases. According to liver disease experts, the main reasons for the increase in serum alanine aminotransferase are:

1. Pathological increase: Liver disease (hepatitis, liver necrosis, fatty liver, liver cancer, etc.), myocarditis, nephritis, pneumonia, tuberculosis, sepsis, encephalitis, meningitis, muscle inflammation, typhoid fever, malaria, cholecystitis, gallstones, bile duct obstruction, colds, influenza, measles, schistosomiasis, lupus erythematosus, hyperthyroidism, diabetes, heart failure, rheumatism, digestive tract diseases, uremia, bone diseases, etc. can all increase ALT.

2. Abuse of health products and supplements. Many health products and supplements can increase alanine aminotransferase.

3. Increased poisoning: Alcohol poisoning, pesticide poisoning, lead, mercury and other heavy metal poisoning, and other acute and chronic poisoning can increase alanine aminotransferase.

4. Physiological increase: pregnancy, fatigue, exercise, mood deterioration, psychological pressure, endocrine disorders, and insufficient blood supply to the heart, liver, and brain can all increase alanine aminotransferase.

5. Drug-induced increase: More than 100 drugs have been found to increase alanine aminotransferase, including psychiatric drugs (chlorpromazine, etc.), anti-tuberculosis drugs (rifampicin, etc.), anti-inflammatory and antibacterial drugs (tetracycline, gentamicin, chloramphenicol, etc.), contraceptives and some traditional Chinese medicines.

High risk

(1) High levels of alanine aminotransferase can cause continuous damage to liver cells and worsen the condition.

(ii) High alanine aminotransferase leads to decreased liver metabolic capacity. When the liver's metabolic capacity decreases, the liver will have to work at overload, which is not conducive to the liver's recovery and may even aggravate liver damage.

(III) High alanine aminotransferase leads to decreased liver detoxification function. Toxins cannot be eliminated from the liver in time, which increases the liver's burden and damages the liver.

No matter what kind of disease it is, if it is not treated in time, it will cause serious harm to the body. Therefore, if the aminotransferase is high and not treated in time, it will cause serious harm to the liver and other organs. Therefore, after understanding the causes and dangers, in order to recover as soon as possible, it is best to choose a large hospital for treatment.