Furazolidone can kill Pylori

The drug furazolidone has certain antibacterial and disinfecting effects, but it must be used for the right disease. If there is really a problem with your pyloric gland, you should still get a check-up first so that you can receive targeted treatment. Don't take some drugs blindly, as this will be bad for your body. You can only take this antibacterial drug if you are confirmed to have a bacterial infection.

Drug interactions

(1) Co-use with tricyclic antidepressants may cause acute toxic psychosis and should be avoided.

(2) This product can enhance the effect of levodopa.

(3) Sympathomimetic amines, tyramine-rich foods, appetite suppressants, monoamine oxidase inhibitors, etc. can enhance the effects of this product.

Pharmacology and Toxicology

This product is a nitrofuran antibacterial drug. It has certain antibacterial effects on both Gram-positive and Gram-negative bacteria, including Salmonella, Shigella, Escherichia coli, Klebsiella pneumoniae, Enterobacter, Staphylococcus aureus, Enterococcus faecalis, Streptococcus pyogenes, Vibrio cholerae, Campylobacter, Bacteroides, etc. It is also active against Trichomonas and Giardia at a certain concentration. Its mechanism of action is to interfere with bacterial oxidoreductase and thus block the normal metabolism of bacteria.

Pharmacokinetics

Only 5% of this product is absorbed orally. When an adult takes 1g at once, the blood concentration is 1.7-3.3mg/L, but a relatively high drug concentration is maintained in the intestine. Part of the absorbed drug is excreted in the urine.

The antibacterial spectrum is similar to that of furanine. Most sensitive to Escherichia coli, Shigella dysenteriae, etc. But it is not easily absorbed by the intestines when taken orally. Used for bacillary dysentery and enteritis. It can also be used for urinary tract infections.

It can be used as a feed additive and was first used in the prevention and treatment of coccidiosis. It mainly acts on the second-generation reproductive bodies of coccidia during their growth process. It can prevent and control Eimeria fragilis, Eimeria toxicophila, and Eimeria acervulina in chickens. In addition to its effects on coccidia protozoa, it is also effective against bacterial dysentery.

Third, long-term use of Sulfadiazine will leave residues in chicken liver, chicken, pork liver, and pork, which will affect human health. Its residual drugs can destroy the human hematopoietic system, causing hemolytic congestion, agranulocytosis, thrombocytopenia, and may also cause peripheral neuritis in humans, and there is no specific drug treatment.

To sum up, the majority of breeders should raise their awareness and stop using Sulfadiazine for the sake of breeding safety and personal health. For those doctors who still use Sulfatil, it is recommended not to use it or use it less. In addition, the baby's immune system and liver are not yet fully developed, and they are particularly sensitive to Sulfadiazine. Therefore, Sulfatil poses a greater potential threat to infants. For the treatment of bacillary dysentery, norfloxacin can be used instead, and for the treatment of protozoan diseases, metronidazole can be used instead.