In recent years, with the development of medical science, experts have found that the efficacy of many drugs is closely related to the duration of medication. This is because the physiological and pathological changes in the human body are related to the circadian rhythm fluctuation phenomenon. Therefore, the best time to take medication should be chosen according to the circadian rhythm fluctuations of the disease to achieve the best therapeutic effect. Blood pressure medications: According to the rhythm of the human body's biological clock, antihypertensive drugs should be taken three times a day, at 7 am, 3 pm and 7 pm respectively. The amount of medicine taken in the morning and evening should be slightly less than that in the afternoon. It is not advisable to take antihypertensive drugs before going to bed at night to prevent low blood pressure and bradycardia, which may lead to cerebral thrombosis. Antibiotics and anti-inflammatory drugs: Antibiotics are excreted quickly, so in order to maintain a certain concentration in the blood, the drug should be taken once every 6 hours. Anti-inflammatory drugs, such as those for patients with rheumatic or rheumatoid arthritis, often experience more severe joint pain in the early morning and morning every day. If you take anti-inflammatory and analgesic drugs, you can increase the dose and take it once in the morning for the best effect, and you can skip the midday dose. Diabetes-lowering drugs: Diabetic patients are most sensitive to insulin in the early morning, and the amount of insulin injected at this time is small and the effect is good. It is best to take methylglycine (D860) orally at 8 am. It has a strong and long-lasting effect. Taking it in the afternoon requires a larger dose to achieve the same effect. Allergy medicine: If cyproheptadine is taken around 7 am, its efficacy can be maintained for 15 to 17 hours, while if taken at 7 pm, it can only last for 6 to 8 hours. Hormone drugs : The human body's response to hormonal drugs also has a time rhythm. Since the peak secretion of adrenal cortex hormone in the human body is around 7 am, the best effect is achieved by giving the drug once at 7 am every day. Antipyretic analgesics: If aspirin is taken around 7 am (after meals), it will be highly effective and lasting. If it is taken at 6 pm or 10 pm, the effect will be less. Cholesterol-lowering drugs: Since the production of cholesterol and other blood lipids in the human body increases at night, patients should take cholesterol-lowering drugs at dinner.
Hypnotic drugs, anthelmintics, contraceptives: It is generally recommended to take it half an hour before going to bed at night. Ranitidine and famotidine, which inhibit gastric acid, can be taken before going to bed every night, because the secretion of gastric acid is less during the day and more at night. |
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