What are the chemotherapy drugs for bladder cancer instillation

What are the chemotherapy drugs for bladder cancer instillation

The drugs for intravesical chemotherapy after bladder cancer surgery include pirarubicin, epirubicin, doxorubicin, hydroxycamptothecin, mitomycin, gemcitabine, etc. The effect of intravesical chemotherapy is related to urine pH, the duration of action of chemotherapy drugs, the dosage of chemotherapy drugs and the concentration of chemotherapy drugs. The concentration of chemotherapy drugs is more important than the duration of action of chemotherapy drugs. It is generally injected into the bladder through a catheter for 0.5-2 hours. Intravesical chemotherapy for bladder cancer is generally used as an adjuvant treatment after transurethral resection of bladder tumors, especially for patients with primary tumors who may not have completely removed the detached tumor cells. Intravesical chemotherapy drugs greatly reduce the recurrence rate of bladder cancer. Intravesical chemotherapy drugs for bladder cancer mainly include doxorubicin, epirubicin, pirarubicin, hydroxycamptothecin, mitomycin, gemcitabine, etc.

Is advanced bladder cancer painful?

Advanced bladder cancer may feel a swollen mass in the lower abdomen and suprapubic region, or it may extensively infiltrate the pelvic lymph nodes, causing lumbosacral pain. This pain can be relieved by taking painkillers. Bladder tumors can invade the urethra, causing certain urination difficulties. Malignant tumors usually present with nausea, loss of appetite, fever, weight loss, anemia, weakness, and malignant diseases. Bladder cancer is a common malignant tumor in the urinary system. Advanced bladder cancer usually refers to bladder cancer that is large in size or has metastasized to the lymph nodes or has metastasized throughout the body, making it impossible to perform radical surgical resection.

How long can you live with early-stage bladder cancer?

If the drug treatment of bladder cancer is ineffective, it is best to perform surgical treatments such as urethral tumor electroresection or cystectomy to remove the diseased tissue in time, but bladder instillation therapy is often needed for adjuvant treatment after surgery to reduce the recurrence rate of cancer. It is not possible to generalize how long a patient can live with bladder cancer. In fact, good life care and clinical treatment for this disease can prolong the patient's life span.

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