Can nasopharyngeal carcinoma be inherited in the family? How to diagnose nasopharyngeal carcinoma

Does nasopharyngeal carcinoma run in the family? How is nasopharyngeal carcinoma diagnosed?

Nasopharyngeal carcinoma usually occurs between the nasopharynx, most commonly at the top, followed by the side and front walls, and least at the bottom. The anatomical location of nasopharyngeal carcinoma is hidden, and the symptoms and signs are variable, which can be easily ignored by patients.

The incidence of nasopharyngeal carcinoma has obvious regional, racial and familial clustering. Nasopharyngeal carcinoma is common in the yellow race, and few Caucasians suffer from this disease. Families with a high incidence of nasopharyngeal carcinoma, such as those who immigrate overseas, still maintain a high incidence trend.

Examinations for nasopharyngeal carcinoma include indirect nasopharyngeal endoscopy, nasopharyngeal fiber endoscopy, nasopharyngeal CT and MRI examinations. Pathological examination is the most important basis for the diagnosis of nasopharyngeal carcinoma.

1. Anterior rhinoscopy After the nasal mucosa is converged, the anterior rhinoscopy can glimpse the posterior nasal cavity and nasopharynx to detect cancer that has invaded or invaded the adjacent nostrils.

2. Indirect nasopharyngeal endoscopy is simple and practical. Check the nasopharyngeal wall in turn, pay attention to the posterior wall of the nasopharyngeal roof and the pharyngeal recesses on both sides, and compare and observe the corresponding parts on both sides. Pay more attention to the asymmetric submucosal protrusions or isolated nodules on both sides.

3. Fiberoptic nasopharyngoscopy During fiberoptic nasopharyngoscopy, 1% ephedrine solution can be used to astringe the nasal mucosa and dilate the nasal passages. Then 1% dicaine solution is used to anesthetize the nasal passages. Then the fiberscope is inserted from the nasal cavity and pushed forward while observing until the nasopharyngeal cavity. This method is simple and the mirror is fixed, but the observation of the posterior nasal cavity and the anterior wall is not satisfactory.

4. Neck biopsy For cases that are not diagnosed by nasopharyngeal biopsy, a neck mass biopsy can be performed. Generally, it can be performed under local anesthesia. During the operation, the earliest hard lymph nodes should be selected, and efforts should be made to remove the entire capsule. If the excisional biopsy is really difficult, a wedge excisional biopsy can be performed at the mass. When removing the tissue, a certain depth must be achieved to avoid squeezing. At the end of the operation, the surgical field must not be sutured too tightly.