How to treat prostate cancer bone metastasis

Prostate cancer is a malignant tumor that occurs in the prostate epithelium and is hereditary. Like other malignant tumors, as the disease progresses, prostate cancer will metastasize. Some patients have bone metastases, so they are naturally concerned about the solution. So, how to treat prostate cancer bone metastasis? Let's take a look below.

There are two types of treatment for prostate cancer bone metastasis. One is that patients with bone metastasis have bone metastasis when the tumor is first discovered. Such patients may respond better to endocrine therapy. The other is that after a period of tumor treatment, the tumor is no longer sensitive to endocrine therapy and develops into hormone-independent or hormone-refractory prostate cancer, with bone metastasis. For the latter, the purpose of treatment for prostate cancer bone metastasis is mainly to relieve bone pain, prevent and reduce the occurrence of bone-related events, improve quality of life, and increase survival rate.

At present, the main purpose of treating prostate cancer bone metastasis and bone pain is to control pain symptoms, prevent and treat complications, and improve the patient's quality of life. There are many methods that can be selected in clinical practice, mainly radiotherapy, traditional Chinese medicine treatment and analgesia treatment. Chemotherapy is not ideal, including:

(1) Symptomatic analgesic drug treatment;

(2) Endocrine therapy and chemotherapy for tumors;

(3) Specific treatment for bone metastasis, such as radiotherapy, radionuclide therapy, and bisphosphonate therapy;

(4) Experimental treatments, such as immunotherapy and gene therapy;

(5) Comprehensive application of the above methods. The following is a brief review of radiotherapy, orthopedic intervention, and analgesic drug therapy.

Radiation therapy for prostate cancer bone metastasis

Indications for radiotherapy of prostate cancer bone metastasis include bone pain, high-risk metastatic lesions with pathological fractures, and neurological complications caused by spinal cord compression. Radiotherapy can relieve bone pain symptoms in most patients. A meta-analysis of the results of multiple prospective studies showed that the overall treatment response rate of various radiotherapy regimens was 65%-100%, but the pain completely disappeared in about 50% of patients. Extending the course of radiotherapy can increase the bone pain relief rate, but it is difficult to achieve for patients with bone metastasis who are expected to have a short survival period and are in poor general condition. The commonly used options are external beam radiotherapy and half-body radiotherapy, and orthopedic intervention can be performed if necessary.

Traditional Chinese medicine treatment for prostate cancer bone metastasis

Regarding the etiology of prostate cancer, a large amount of clinical data suggests that it is related to sex hormones. It is related to the imbalance of the ratio of estrogen to androgen in the circulation, especially the changes in androgen. At the same time, some studies have also shown that the incidence rate can also increase after high fat intake, environmental pollution, and gonococcal infection. Recently, British scholars have found that excessive drinking of coffee and alcohol is also related to the occurrence of prostate cancer.

There are many methods to treat bone metastasis of prostate cancer. How to treat bone metastasis of prostate cancer still requires comprehensive treatment based on the patient's condition. Patients should not have too much psychological burden, but should actively cooperate with doctors for diagnosis and treatment and determine specific treatment strategies. Only in this way can the disease be controlled to the greatest extent.