How to treat lung cancer bone metastasis? The best treatment for lung cancer bone metastasis

Lung cancer is generally difficult to treat. So what is the best treatment for lung cancer bone metastasis? When a patient has bone metastasis, what are the symptoms of lung cancer metastasis? Why do people get lung cancer? What are the pathogenic factors of lung cancer? Let the experts take you to understand. ​

Good treatment for lung cancer bone metastasis. Lung cancer bone metastasis is mostly osteolytic damage. Small cell undifferentiated carcinoma and a small amount of adenocarcinoma may show osteoblastic damage. Among patients, 86% are osteolytic damage, 6.9% are osteoblastic damage, and 6.9% are mixed damage. The incidence of primary lung cancer complicated by hypercalcemia is 26%. Hypercalcemia in cancer patients is not primarily caused by the increase in osteoclast activity caused by bone metastasis, which causes calcium in the bones to enter the extracellular fluid. It may be caused by pTHrp excreted by the tumor and has nothing to do with bone metastasis. Therefore, the incidence of hypercalcemia is not high in lung cancer patients with bone metastasis. Chemotherapy Systemic chemotherapy can control the development of bone metastasis and relieve pain while treating the primary lesions in the lungs. Therefore, it can not only relieve pain, but also kill cancer cells and control their growth. In particular, the combined chemotherapy regimen based on high-dose cisplatin is more effective. In some cases, when rechecking the X-ray film, it was found that the bone metastasis disappeared and new bone cortex was formed. Because when lung cancer cases have bone metastases, there may also be potential micrometastases in other organs of the body. Therefore, combined systemic chemotherapy can treat bone metastases while also having a therapeutic effect on other potential metastases. There is also zoledronic acid, which is mainly used to treat bone metastases. Radiotherapy Radiotherapy can be divided into several methods such as cobalt-60 irradiation, deep x-ray machines and linear accelerators. For isolated bone metastases, after the lung lesions are controlled and stabilized by chemotherapy, high-dose, short-course radiotherapy can be given to relieve pain, kill cancer cells and control the development of lesions. About 50% of patients can completely relieve pain after radiotherapy, and about 75% of patients can significantly reduce pain. ​

Biological immunotherapy (still in the experimental stage) Biological immunotherapy is a new type of treatment method for autoimmune cancer. It is mainly a new type of treatment method for autoimmune cancer. It uses biotechnology and biological preparations to culture and amplify immune cells collected from the patient's body in vitro and then return them to the patient's body to stimulate and enhance the body's own immune function, thereby achieving the purpose of treating tumors. There are no clinical medical success cases of biological immunotherapy. Targeted therapy radionuclide internal irradiation therapy is actually a targeted treatment for bone metastasis of lung cancer. ​

Patients with multiple bone metastases throughout the body are not suitable for radiation therapy. In this case, radionuclide therapy can be used. Radionuclides can reduce bone damage and dissolution caused by bone metastasis, and can eliminate or alleviate the severe pain caused by bone metastasis, while inhibiting the development of bone metastases. However, because it can also cause bone marrow suppression, it is generally not suitable for use with chemotherapy, and white blood cell changes must be observed regularly. Bone metastasis of lung cancer also needs to be treated in combination with the symptoms of lung cancer. Lung cancer is mainly divided into two categories, one is small cell lung cancer and the other is non-small cell lung cancer. Small cell lung cancer cannot use targeted therapy; non-small cell lung cancer includes squamous cell carcinoma, adenocarcinoma, squamous cell carcinoma and large cell carcinoma. Drug treatment Bisphosphonate drug treatment, endocrine and molecular targeted therapy and other anti-tumor treatments. Gamma Knife Treatment A brief introduction to the characteristics of Gamma Knife treatment of lung cancer. ​

Provide patients and their families with information and choose better treatment methods. 1. Generally, lung cancer is sensitive to radiation, the effect is significant, the price is reasonable, and patients can easily accept it. 2. No thoracotomy, local irradiation, less damage; 3. It is a type of radiotherapy, which has a certain impact on surrounding tissues, and the human body has a limited tolerance dose. It is not effective for larger tumors and multiple tumors; 4. It can be implemented alone or in combination with argon-helium knife, chemotherapy or surgical therapy. 5. The repeatability is slightly poor, and it loses its effect once the tumor is not sensitive to it. 6. The success rate is high and the complications are few; the patient recovers quickly and does not need to be hospitalized; in this case, gamma knife treatment can be performed, but further diagnosis and location of the tumor are required. Symptoms of lung cancer metastasis Lung cancer metastasis is very scary, which means that lung cancer has reached the late stage and will threaten life if it is not treated. So, what are the symptoms of lung cancer metastasis? 1. Brain metastasis of lung cancer Lung cancer patients experience headaches, vomiting, visual impairment, and personality and temper changes without reason. This may be caused by intracranial hypertension or cranial nerve damage caused by lung cancer metastasis to the brain. Common in small cell lung cancer and adenocarcinoma types. Headache is a common symptom. Vomiting often occurs when the headache is severe, and is characterized by projectile vomiting. Visual impairment indicates that the tumor has affected, compressed or invaded the optic nerve. In addition to the above common symptoms, brain metastasis of lung cancer may also cause recurrence, paroxysmal blackouts, cataplexy, impaired consciousness, increased blood pressure, slow pulse, and in severe cases, brain herniation due to tumor compression may lead to respiratory arrest, endangering the patient's life.