Is fungus a medicine?

Many people are familiar with black fungus. This ingredient is delicious whether it is stir-fried or served cold. The most common way to eat it is to serve it cold. Of course, stir-fried black fungus is also very delicious, such as stir-fried black fungus with garlic, stir-fried black fungus with jellyfish, etc. The reason why fungus is so popular, besides its taste, is also its nutritional value. It has the effect of replenishing qi and blood and lowering blood pressure, but it cannot replace medicine.

Pharmacological value

Indications

Efficacy: Nourishes qi and blood; moistens the lungs and relieves cough; stops bleeding; lowers blood pressure; fights cancer.

Indications: Qi deficiency and blood deficiency; chronic cough due to lung deficiency; hemoptysis; epistaxis; bloody diarrhea; hemorrhoidal bleeding; metrorrhagia in women; hypertension; fundus hemorrhage; cervical cancer; vaginal cancer; and bruises and pains.

Effects on the circulatory system

1. Anticoagulant effect. 1ml/100g of 300% fungus decoction was administered intragastrically for 20 consecutive days. The experimental results showed that fungus could prolong the partial thromboplastin time of white clay by 12.06s, increase the activity of plasma antithrombin III, and have a significant anticoagulant effect. Black fungus polysaccharide 50 mg/kg given to mice by intravenous injection, intraperitoneal injection, and gavage all had a significant anticoagulant effect; in in vitro experiments, black fungus polysaccharide also had strong anticoagulant activity.

2. Anti-platelet aggregation effect. The phosphate-buffered saline extract of black fungus significantly inhibited ADP-induced platelet aggregation in a test tube and blocked the release of 5-hydroxytryptamine from platelets activated by ADP below 16 μmol/L. The active ingredient of black fungus's antiplatelet effect is water-soluble. After taking 70g of black fungus orally, people will begin to experience decreased platelet function within 3 hours and last for 24 hours. The acid extract of Auricularia auricula mycelium can significantly inhibit ADP-induced platelet aggregation in rats in vivo (10g/kg intravenous injection or 10g/kg gavage for 15 consecutive days in rats) and in vitro (25mg/ml, 50mg/ml and 100mg (mycelium)/ml). Oral administration of 5g/kg and 7g/kg of the alcohol extract for 15 days can significantly shorten the electrophoresis time of red blood cells. The results of the intraperitoneal injection test of black fungus acidic heteropolysaccharide in mice showed that the polysaccharide has the effects of promoting leukocyte increase, anti-coagulation and reducing platelets, and its activity increases with the decrease of polysaccharide molecular weight and uronic acid content, that is, the biological activity depends on the solubility of the polysaccharide in water.

3. Anti-thrombosis. Oral administration of 18.5 mg/kg of Auricularia auricularia polysaccharide to rabbits can significantly prolong the formation time of specific thrombus and fibrin thrombus, shorten the length of thrombus, reduce the wet weight and dry weight of thrombus, reduce the number of platelets, reduce the platelet adhesion rate and blood viscosity, and significantly shorten the euglobulin dissolution time of guinea pigs, reduce plasma fibrinogen content, and increase plasmin activity. The results show that Auricularia auricularia polysaccharide has a significant anti-thrombotic effect.

Enhances immune function

Black fungus polysaccharide can increase the spleen index, half hemolysis value (HC50) and rosette formation rate of mice, promote macrophage phagocytosis and lymphocyte transformation, etc. Intraperitoneal injection of 250 mg/kg of Auricularia auriculariae mycelium into mice for 7 consecutive days can significantly increase the percentage of peripheral blood T lymphocytes; subcutaneous injection of 400 mg/kg and 800 mg/kg for a total of 7 days can reduce the half hemolysis value HC50 caused by cyclophosphamide and return it to normal.

Promote biosynthesis

100 μg of black fungus polysaccharide has a significant promoting effect on the synthesis of deoxyribonucleic acid and RNA in human lymphocytes. Intraperitoneal injection of black fungus polysaccharide to mice at a dose of 100 mg/kg for 4 consecutive days had a weak promoting effect on the incorporation of 3 H leucine into mouse serum proteins.

Reduce arteriosclerosis

Continuous oral administration of 30 g/kg of wood ear decoction for 20 days and 28 mg/kg of wood ear polysaccharide for 8 days can significantly reduce the levels of serum triglycerides (triglycerides) and total cholesterol (TC) in hyperlipidemic rats, increase the ratio of serum high-density lipoprotein cholesterol (HDL-C) to total cholesterol, and have a cholesterol-lowering effect. Oral administration of 180 mg/kg of Auricularia auricula polysaccharide can prevent the formation of hypercholesterolemia in mice caused by high cholesterol. When feeding cholesterol, 2.5 g of black fungus was added to each rabbit every day for 90 days. It reduced the levels of plasma cholesterol, lipid peroxide (LPO), and thromboxane A2 (TXA2) in rabbits, increased the ratio of prostacyclin/thromboxane A2 (PGI2/TXA2), and alleviated atherosclerosis.

Delaying aging

Giving rabbits 2.5g of black fungus daily for 90 days can reduce the levels of oxygen free radicals, lipofuscin in liver, heart and brain tissues, plasma lipid peroxides, and plasma cholesterol in rabbits with atherosclerosis, and alleviate the effects of atherosclerotic lesions. These results suggest that black fungus may lower plasma cholesterol and reduce the formation of lipofuscin, a lipid peroxidation product, to maintain normal cell metabolism and thus have an anti-aging effect. Using chemiluminescence analysis, the scavenging effect of 50μl, 800μl, and 1000μl of 2.5% black fungus water extract on H2O2 or superoxide radicals (O-2) produced by enzyme systems and non-enzymatic systems was studied. The scavenging ability showed a dose-effect relationship with the dosage, indicating that the black fungus water extract contains ingredients with antioxidant effects.

value

Intraperitoneal injection of 100 mg/kg of black fungus polysaccharide for 7 consecutive days can prolong the average swimming time of mice in water by 50.40%, and enhance the anti-fatigue ability of mice; it can also significantly reduce the lipofuscin content in the myocardial tissue of mice; it can significantly increase the specific activity of superoxide dismutase (SOD) in the brain and liver tissue of mice; it has a significant inhibitory effect on the activity of monoamine oxidase B (MAO-B) in the isolated brain of mice, and the inhibitory intensity increases with increasing concentration, and can increase the flying ability of fruit flies. Black fungus polysaccharide can significantly prolong the average lifespan of fruit flies, which is 1.26 times that of the control group. After oral administration of black fungus polysaccharide for 40 days, the lipofuscin content of fruit flies

Anti-radiation and anti-inflammation

Intraperitoneal injection of 100 mg/kg of Auricularia auricularia polysaccharide into mice for 7 consecutive days had an antagonistic effect on 60Co γ-ray irradiation, increasing the survival rate of mice by 1.56 times. Intraperitoneal injection of 60 mg/mouse had a certain anti-inflammatory effect on plantar swelling caused by egg white in rats.

Anti-ulcer effect

Black fungus polysaccharide, administered intragastrically at 70 mg/kg per day for 2 consecutive days, can significantly inhibit the formation of stress ulcers in rats; administered intragastrically at 165 mg/kg per day for 12 consecutive days, can promote the healing of acetic acid-type gastric ulcers, with no significant effect on gastric acid secretion and pepsin activity.

Hypoglycemic effect

Oral administration of 33mg/kg or 100mg/kg of Auricularia auricula polysaccharide can significantly reduce the blood sugar level of alloxan diabetic mice. The blood sugar lowering effect is most significant 4 to 7 hours after oral administration of the polysaccharide. It can also reduce the amount of water consumed by diabetic mice.

Impact on fertility

When 8.25 mg/kg of black fungus polysaccharide was injected intraperitoneally into mice, the anti-implantation and anti-early pregnancy effects were the most obvious, and the effect on terminating mid-term pregnancy was slightly worse, but it was ineffective for the transportation of pregnant eggs.

Anti-cancer, anti-mutation

The inhibition rate of hot water extract of Auricularia auricula on Swiss mouse sarcoma S180 is 42.5% to 70%, and the inhibition rate on Ehrlich ascites carcinoma is 80%. Auricularia auriculariae polysaccharide 200 mg/(kg·d) for 10 consecutive days can counteract the increase in bone marrow micronucleus rate in mice induced by cyclophosphamide.

Antibacterial effect

The blackthorn fungus isolated from fungus has antifungal effects.

Remove dark spots

Take 30 grams of black fungus and 20 red dates. Wash the black fungus, remove the core of the red dates, add appropriate amount of water, and cook for about half an hour. Once a day in the morning and after dinner. Regular consumption can keep your face youthful and remove freckles, tone and plump your muscles, and can also be used to treat facial dark spots and thinness. The black fungus in this recipe is recorded in Compendium of Materia Medica as being able to remove dark spots on the face. Black fungus can moisturize the skin and prevent skin aging. Jujubes can nourish the spleen and moisturize the skin, and help black fungus eliminate dark spots.

Cleanse the stomach and intestines and protect against radiation

The gelatin in black fungus can absorb dust, impurities and radioactive substances remaining in the human digestive system, concentrate them and excrete them out of the body, thereby playing a role in clearing the stomach, cleansing the intestines and protecting against radiation.

Dissolving function of gallstones and kidney stones

Because the plant alkaloids it contains have the characteristics of promoting the secretion of various glands in the digestive tract and urinary tract, the plant alkaloids can cooperate with these secretions to catalyze stones and lubricate the intestines.