What should I do if I find abdominal wall fibroma? It is recommended to go to a regular hospital for examination as soon as possible

There are many types of abdominal wall fibroma, the most common of which are benign fibroma, borderline fibroma between benign and malignant, and malignant tumor. If it is a benign solitary fibroma, it grows very slowly and will not have a big impact on the human body. When the fibroma grows larger, it can be treated with surgical resection, radiotherapy, endocrine therapy, adjuvant chemotherapy, etc.

What should I do if I find abdominal wall fibroma? It is recommended that patients go to a regular hospital for examination as soon as possible and receive timely treatment, because abdominal wall fibroma may worsen. If abdominal wall fibroma worsens, it may cause cancer, and cancer is very harmful to the body. There are currently several ways to deal with abdominal wall fibroma.
1. Surgical resection
1. Local excision of tumor <br/>The local recurrence rate of simple local excision of tumor can be as high as 70%. As early as 1889, Douffier advocated extensive and thorough excision of abdominal wall desmoid tumors.
2. Tumor resection <br/>Generally, the resection range should include at least 3 cm of normal tissue around the tumor, and the peritoneum should be removed at the same time, which is extremely important to prevent postoperative recurrence. Abdominal wall defects can be repaired with artificial synthetic patches such as MarlexMesh, polypropylene or polytetrafluoroethylene patches, which have good therapeutic effects.
3. Frozen sections <br/>To clarify the nature of the tumor and the extent of resection and to prevent residual lesions, routine frozen sections are performed during surgery. For larger tumors or giant desmoid tumors of the abdominal wall, multiple frozen sections should be made at the resection margin, especially the longitudinal resection margin, and the incision can only be closed after confirming that there is no residual tumor tissue.
2. Radiotherapy <br/>Whether radiotherapy alone or as an adjuvant to surgery, it is an effective method for treating abdominal wall desmoid tumors. To reduce recurrence, radiotherapy can be used as an adjuvant treatment before and after surgery for larger tumors, or as a remedy when the surgical resection range is insufficient and the tumor cannot be removed. Radiotherapy is not recommended for patients with negative resection margins. The dose of radiotherapy is 50-60Gy. It is generally recommended that patients with positive resection margins receive 50Gy of radiotherapy after surgery, and unresectable tumors are irradiated with a dose of about 56Gy. The condition of 75% of patients can be controlled. The radiation dose is related to the occurrence of complications. When a dose of 56Gy or less is used, 5% of patients will have complications in 15 years, and a larger dose will cause complications in 30% of patients.
3. Endocrine therapy Basic research has found that estrogen is closely related to the growth of abdominal wall desmoid tumors. Therefore, some scholars have advocated the use of endocrine therapy in recent years. Wilcken et al. reported that the efficacy of endocrine therapy for single tumors is 60%. For patients with estrogen receptor-positive resection specimens, tamoxifen can be the first choice, and luteinizing hormone-releasing hormone can be selected as the second-line drug. The combination of the two has an efficacy of 50%. There are also successful case reports of the use of progesterone, testosterone and prednisone. However, some people believe that the exact role of endocrine therapy is still uncertain and further observation and research are needed.
IV. Adjuvant chemotherapy <br/>Chemotherapy is suitable for young people and children with macroscopic residual tumors, progressive disease, and failure of surgery and radiotherapy. It may help reduce the local recurrence rate and effectively control the progression of the disease. Commonly used chemotherapy drugs include vincristine, methotrexate (MTX), doxorubicin (ADM, adriamycin) and actinomycin D (actinomycin D, dactinomycin). The most effective treatment is vincristine and methotrexate, with acceptable side effects, and treatment should be continued for at least 20 weeks.
Other drugs include cyclic adenosine monophosphate regulators (such as theophylline, chlorothiazide, vitamin C, etc.), non-steroidal anti-inflammatory drugs (such as indomethacin), etc.