Come and take a look at which diseases lead to the occurrence of tumors?

Nowadays, more and more diseases are appearing in people's lives, and the first to be affected is tumor. Tumor is a disease that everyone is familiar with, but once you hear about it, you will feel scared and worried. In our industrialized life, there are many substances that can cause cancer directly or indirectly. Here are some carcinogenic factors. Indirect chemical carcinogens: polycyclic aromatic hydrocarbons, aromatic amines and aminoazo dyes, nitrosamines, fungal toxins. Direct chemical carcinogens: These carcinogens can cause cancer without being activated in the body, such as alkylating agents and acylating agents.

Nitrosamines

This is a type of chemical carcinogen that is highly carcinogenic and can cause a variety of cancers in animals. It is found in high levels in spoiled vegetables and foods, and can cause tumors in the digestive system, kidneys and other organs.

PAHs

Benzopyrene is a representative of this type of carcinogen. Applying it to the skin of animals can cause skin cancer, and injecting it subcutaneously can induce sarcoma.

Trialkylating agents

Such as mustard gas, cyclophosphamide, etc., which can cause leukemia, lung cancer, breast cancer, etc.

Tetrachloroethylene

Polyvinyl chloride, the most widely used plastic at present, is made by polymerizing vinyl chloride monomers. It can induce tumors in the lungs, skin, bones, etc. Epidemiological surveys of plastic factory workers have confirmed that vinyl chloride can cause hemangiosarcoma of the liver, with a latency period of more than 15 years.

5 Certain metals

Elements such as chromium, nickel, and arsenic can also cause cancer.

The mechanism of chemical carcinogens causing human tumors is very complex. A few carcinogens can directly induce tumors after entering the human body. These substances are called direct carcinogens. Most chemical carcinogens need to undergo metabolic activation or biotransformation in the body to become final carcinogens with carcinogenic activity before they can cause tumors. These substances are called indirect carcinogens. Tumors caused by radiation include: thyroid tumors, lung cancer, bone tumors, skin cancer, multiple myeloma, lymphoma, etc.

Physical carcinogens

Ion radiation causes various cancers. Long-term thermal radiation also has a certain carcinogenic effect. Metal elements such as nickel, chromium, cadmium, and beryllium also have carcinogenic effects on humans. Clinically, some tumors are also related to trauma. Patients with osteosarcoma, testicular sarcoma, and brain tumors often have a history of trauma. Another type of foreign body related to tumors is parasites.

Viruses and bacteria cause cancer

1RNA oncogenic virus: It integrates genetic material into host cell DNA through transduction and insertion mutation, and transforms the host cells. There are two mechanisms of carcinogenesis: ① acute transforming virus ② chronic transforming virus.

2DNA tumorigenic viruses: Common ones include human papillomavirus HPV, which is closely related to human epithelial tumors, especially squamous cell carcinoma in the cervix and anogenital region. Epstein-barr virus EBV is closely related to Burkitt lymphoma and nasopharyngeal carcinoma. Epidemiological surveys show that hepatitis B is closely related to hepatocellular carcinoma. Chronic gastritis caused by Helicobacter pylori is related to the occurrence of low-grade malignant B-cell lymphoma of the stomach.