What are the commonly used anti-pancreatic cancer drugs

What are the commonly used anti-pancreatic cancer drugs? Speaking of pancreatic cancer, let us all think about it carefully. This disease is a common digestive tract malignancy. Its appearance can directly threaten the life and health of patients, and its clinical mortality rate is high. It is a cancer with the worst prognosis. The treatment methods are mainly surgery, chemotherapy, radiotherapy and drugs. So, let's take a look at what are the anti-pancreatic cancer drugs?

1. Gemcitabine: Compared with other drugs, gemcitabine has fewer side effects while maintaining similar efficacy and is well tolerated by patients. Combination chemotherapy based on gemcitabine benefits patients with pancreatic cancer at all stages.

2. 5-Fluorouracil: It was a key drug for the treatment of pancreatic cancer before the advent of gemcitabine. Recent studies have shown that the "FOLFIRINOX" quadruple chemotherapy drug composed of 5-fluorouracil, folinic acid, oxaliplatin, and irinotecan has better efficacy in metastatic pancreatic cancer than gemcitabine alone, but its application is limited due to the increased toxic side effects.

3. Molecular targeted drugs: Intracellular tyrosine kinase phosphorylation is an important link in the survival and proliferation of tumor cells. Inhibition of tyrosine kinase phosphorylation can effectively inhibit tumor growth. Representative drugs include erlotinib, sunitinib, etc., and clinical trials of sunitinib for the treatment of pancreatic neuroendocrine tumors have been carried out.

4. Stromal removal therapy drugs: Pancreatic cancer contains abundant tumor stroma but few blood vessels, which makes it difficult for chemotherapy drugs to reach the local tumor, thus affecting the efficacy. Studies have shown that anti-angiogenic drugs such as sorafenib and sunitinib are basically ineffective. Drugs with potential vascular normalization effects such as metformin may improve the efficacy of gemcitabine, but the actual effect still needs to be evaluated.

In recent years, with the continuous development of traditional Chinese medicine, it has also achieved good results in the treatment of cancer, helping many patients reduce pain and prolong their lives. For example, in clinical practice, it is safe, non-toxic, low-cost, painless, and has significant efficacy, and is well received by patients and their families. It has a good effect in inhibiting tumors and can improve the patient's immune function.

In short, when pancreatic cancer patients choose treatment methods, they should also choose appropriate treatment plans and drugs based on their own conditions. No matter which method or drug treatment they choose, they should be used throughout the treatment to improve the cure rate and prolong the survival period. In addition, pancreatic cancer patients should also maintain a good attitude, do a good job of nursing, provide adequate nutritional support, and help patients build confidence in defeating the disease.