What are the causes of small cell lung cancer

What are the causes of small cell lung cancer? Most people think that this disease is untreatable. In fact, this disease can be cured with timely treatment in the early stages of the disease. Many people become more serious because they ignore the treatment time of this disease. Let's learn about the causes of small cell lung cancer!

Smoking is the main risk factor for small cell lung cancer, and SCLC is closely related to smoking. According to a summary analysis of smoking and lung cancer worldwide from 1970 to 1999, small cell lung cancer is positively correlated with smoking intensity (amount of smoking) and duration, and the relationship with SCLC is most obvious.

In the past few decades, there have been many studies on the molecular mechanism of SCLC, suggesting that the occurrence of SCLC may involve the participation of multiple genes. Some studies have shown that the tumor suppressor gene p53, RB gene (neuroblastoma gene), oncogene Bcl-2 gene, Myc gene, PI3K/AKT/mTOR signal transduction pathway, etc. are all related to the occurrence of SCLC.

The treatment of small cell lung cancer is mainly chemotherapy, which can be combined or sequentially with radiotherapy. For less than 5% of early-stage patients limited to the lung parenchyma, surgical treatment is considered. Limited-stage SCLC is mainly treated with synchronous chemoradiotherapy or chemotherapy and radiotherapy sequentially. Synchronous chemoradiotherapy is better than sequential treatment. Synchronous chemoradiotherapy should be performed as early as possible, and preventive whole-brain radiotherapy should be given. Preventive whole-brain radiotherapy has significant benefits for survival. Extensive-stage SCLC is mainly treated with chemotherapy, and local or metastatic lesions are treated at an elective time.

Patients should eat a light diet during chemotherapy, avoid greasy, indigestible and fried foods. Eat more fresh vegetables and fruits, eat small meals frequently, and combine foods reasonably, diversify the diet, and eat a balanced diet. During the intervals between radiotherapy and chemotherapy, pay attention to avoid fatigue, rest, and regular work and rest to avoid infection.