How to maintain after glioma is cured

We all know the seriousness of tumors. Gliomas are indolent tumors. If we want to effectively control them, we need to make a lot of efforts. Therefore, after we get sick, we must formulate a reasonable treatment plan in time to cure it. Gliomas can only be cured clinically and cannot be completely cured. How to maintain the condition after gliomas are cured?

Treatment principles: try to completely remove the tumor; if it is difficult to completely remove the tumor, do subtotal resection; if the tumor cannot be removed or the intracranial pressure is too high, decompression under the temporalis muscle, decompression craniectomy or shunt surgery can be performed. Postoperative radiotherapy.

1. Surgery: Gliomas are characterized by infiltrative growth with no obvious boundary with normal brain tissue. Most of them are not limited to one lobe of the brain and penetrate deep into the brain tissue like fingers. In theory, it is impossible to completely remove them by surgery. Some tumors growing in important parts such as the brainstem cannot be operated on at all. Therefore, the purpose of surgical treatment can only be limited to the following five aspects: (1) Clarify the pathological diagnosis. (2) Reduce the tumor volume and reduce the number of tumor cells. (3) Improve symptoms and relieve symptoms of high intracranial pressure. (4) Prolong life and create opportunities for other comprehensive treatments. (5) Obtain tumor cell dynamics data to provide a basis for finding effective treatments.

2. Radiotherapy: Suitable for patients with grade 2 glioma over 45 years old with clear residual tumor after surgery, or patients with grade 3 or 4 glioma. For patients with grade 2 glioma under 45 years old, even if the tumor is not completely removed, a wait-and-see attitude can still be adopted.

3. Chemotherapy: It is suitable for patients with recurrent secondary gliomas and postoperative treatment of patients with grade 3 and grade 4 gliomas. Chemotherapy is often used for highly malignant brain gliomas. For metastatic brain tumors, the sensitivity of treatment depends on the sensitivity of its primary lesions outside the central nervous system to chemotherapy. Chemotherapy regimens that are effective for primary lesions outside the central nervous system are also sensitive to brain metastases. There are two problems with chemotherapy drugs: the blood-brain barrier and the sensitivity of tumors to drugs.

4. Commonly used drugs: Diqing, cisplatin + nimustine hydrochloride

Traditional Chinese medicine: Cidan Capsules, Xiaoaiping, Jinlong Capsules. Commonly used chemotherapy drugs: ACNU (nicotinamide ammonia mustard), BCNU (carbomustine), CCNU (cyclohexyl lomustine), MeCCNU (methyl CCNU), others include fluorouracil (5FU), cisplatin (DDP), carboplatin (CBP) and methyl procarbazine (PCZ). Combination chemotherapy: PCV (methyl procarbazine + CCNU + VCR), hydroxyurea + BCNU, BCNU + cisplatin. The effective rate is between 20%-40%.

It is very difficult to completely cure brain glioma. Since the treatment of the brain is very difficult, brain glioma is a more serious disease, more difficult to treat, and it is easy to relapse, so everyone should treat it seriously to avoid recurrence.