What is the percentage of glioma cure rate

I believe everyone knows that glioma is a common malignant tumor disease. It is very harmful, difficult to treat, and prone to recurrence. This troubles most patients. Therefore, many patients want to know what the cure rate of glioma is. The following editor will answer this question for everyone.

Glioma, also known as glioma, is a tumor that occurs in the neuroectoderm. There are two types of tumors that occur in the neuroectoderm: one is formed by mesenchymal cells, called glioma; the other is formed by parenchymal cells, called neuronal tumor.

Since these two types of tumors cannot be completely distinguished from each other in terms of etiology and morphology, and gliomas originating from interstitial cells are much more common than neuronal tumors originating from parenchymal cells, neuronal tumors are included in gliomas and are collectively referred to as gliomas.

At present, the treatment of glioma at home and abroad generally includes surgery, radiotherapy, chemotherapy, X-knife, gamma knife, etc. Surgery: Surgical treatment is based on the growth characteristics of glioma. In theory, it is impossible to completely remove it by surgery. Some tumors growing in important parts such as the brainstem cannot be operated on at all. Therefore, the purpose of surgical treatment can only be limited to the following 5 aspects:

① Clear pathological diagnosis;

②Reduce tumor volume and reduce the number of tumor cells;

③Improve symptoms and relieve symptoms of high intracranial pressure;

④ Prolong life and create opportunities for other subsequent comprehensive treatments;

⑤ Obtain tumor cell dynamics data to provide a basis for finding effective treatments.

Radiotherapy: Radiotherapy is almost the routine treatment for all types of gliomas, but the evaluation of the efficacy varies. Except for medulloblastoma, which is highly sensitive to radiotherapy, and ependymoma, which is moderately sensitive, other types are not sensitive to radiotherapy. Some observations believe that the prognosis of radiotherapy and non-radiotherapy is the same. In addition, the impact of radiation-induced radiation necrosis on brain function should not be underestimated.

X-knife and γ-knife are both in the category of radiotherapy. Due to the location of the tumor, the size of the tumor (generally limited to less than 3 cm) and the sensitivity of the tumor to radiation, the treatment scope is limited. At present, it is believed that gliomas, especially malignant astrocytic grade III-IV or glioblastomas, are not suitable for R-knife treatment. However, with the continuous exploration of glioma treatment by Gamma Knife doctors, Gamma Knife dose-fractionated treatment of large gliomas with a tumor diameter of more than 3 cm has achieved good results in clinical practice.

Chemotherapy: In principle, it is used for malignant tumors, but chemotherapy drugs are limited by the blood-brain barrier and drug toxicity and side effects, and the efficacy is still uncertain. Commonly used BCNU, CCNU, VM-26, etc. have an effective rate of less than 30%.