What are the symptoms of hamartoma

What are the symptoms of hamartoma? This is a question that people are more concerned about. Hamartoma is a relatively hidden disease, and most hamartomas are discovered during physical examinations. Because early hamartomas have almost no symptoms or signs, they are easily ignored by patients. So, what are the symptoms of hamartoma? Let's find out together.

Hamartoma is a solid space-occupying lesion, also known as angiomyolipoma (RAML), which is a benign tumor. This disease is an autosomal dominant genetic disease and is a type of lipoma. It is composed of thick-walled blood vessels, smooth muscle and mature adipose tissue and can occur singly, multiple times or bilaterally. Usually, B-ultrasound and CT examinations have a high positioning and qualitative diagnosis rate for renal tumors.

Most hamartomas occur in people over 40 years old, and are more common in men than in women. The vast majority of hamartomas (about 80% or more) grow in the periphery of the lungs, close to the visceral pleura of the lungs, and sometimes protrude from the surface of the lungs.

Most patients with hamartomas have no symptoms. The main reasons for the symptoms are mostly related to the location, size, number, growth rate, and relationship between the hamartoma and surrounding organs. During the physical examination, it is often found that some patients may have the following symptoms due to the tumor itself, increased pressure in the tumor, infection, etc.:

1. Proteinuria: Generally, the amount is not much, and the urine volume in 24 hours will not exceed 2g. Nephrotic syndrome will not occur.

2. Hypertension: The tumor compresses the kidneys, causing renal ischemia, increasing renin secretion, and causing hypertension. When renal function is normal, more than half of the patients have hypertension, and the incidence of hypertension is even higher when renal function is impaired.

3. Decreased renal function: Due to the tumor's space occupation and compression, the normal renal tissue is significantly reduced and the renal function progressively declines.

4. Discomfort or pain in the waist and abdomen: The reason is that the enlarged and expanded kidney increases the tension of the renal capsule, pulls the renal pedicle, or compresses the adjacent organs. In addition, the large size of the renal hamartoma causes the kidney to become heavy, which can also cause pain in the waist. The pain is characterized by dull pain, fixed on one side or both sides, radiating to the lower part and the waist and back. If there is bleeding in the tumor or secondary infection, the pain will suddenly intensify. If the urinary tract is blocked by stones or blood clots after bleeding, renal colic may occur.

5. Hematuria: It can be manifested as microscopic hematuria or macroscopic hematuria. The attack is cyclical. The back pain often worsens during the attack. Vigorous exercise, trauma, and infection can induce or aggravate it.

6. Abdominal mass: This is sometimes the main reason for patients to seek medical treatment. Sixty to eighty percent of patients can feel enlarged kidneys.