What are the causes of pituitary tumors

Pituitary tumors need to be treated promptly. They can cause abnormal hormone secretion and affect a person's normal fertility and growth and development. Many patients often suffer from headaches due to increased intracranial pressure. During detailed examinations, it is discovered that they are caused by pituitary tumors. So, what are the causes of pituitary tumors? Let's take a look.

Hypothalamic regulatory dysfunction is the cause of most of the patients clinically. This is because hypothalamic regulatory dysfunction will lead to an increase in hypothalamic polypeptide hormones, which will directly promote the proliferation of pituitary cells. If the GHRH gene is transplanted at this time, it will directly induce the proliferation of rat GH cells, thereby causing the formation of real pituitary tumors. This cause of disease will also lead to a lack of inhibitory factors, which can also promote the occurrence of tumors. Therefore, it is said that the occurrence of this disease is related to the hypothalamic regulatory dysfunction.

Pituitary cells themselves are defective, because pituitary adenoma itself comes from a mutated cell. When a cell mutates, clonal expansion or self-mutation will occur, leading to cell replication. In this case, if there are some external triggering factors involved or lack of inhibitory transport, it will lead to tumor formation. Oncogenes are actually a type of gene that affects the normal growth of residual cells. Some oncogene products are growth factors and receptors, and are also involved in the transmission of growth signals within cells. Therefore, abnormal expression can also lead to abnormal cell proliferation.

The above are the common causes of pituitary tumors. I hope these contents can allow everyone to understand more about this disease. After understanding these, once you find symptoms of suspected disease in your daily life, you should pay great attention to it and go to the hospital for treatment in time, because timely treatment is very beneficial to the cure of the disease.