What to do if you have mild osteosarcoma

Many young people are diagnosed with osteosarcoma, which is a big blow to patients. It affects their lives and studies, and also causes great economic losses to their families. In fact, osteosarcoma is not as terrible as patients imagine. It can be cured with active treatment. So what should we do with mild osteosarcoma?

Chemotherapy is an important adjuvant treatment for osteosarcoma. High-dose chemotherapy combined with multiple drugs can kill the tumor locally. Preoperative chemotherapy can cause tumor cell necrosis, tumor shrinkage, disappearance of edema and new tumor blood vessels in the reaction area, and clearer boundaries of tumor calcification. Clinically, the patient's pain is reduced or disappears, the tumor becomes smaller, the joint range of motion increases, and AKP can be reduced to normal.

High-dose chemotherapy is also an effective method for systemic treatment of osteosarcoma. Chemotherapy can kill micro-metastases in the lungs and throughout the body. This treatment should be carried out early. Micro-lesions are more sensitive to chemotherapy than large tumors. Adjuvant chemotherapy can reduce the number of tumors in the lungs and delay their appearance. The key to prolonging the survival of patients with lung metastasis is to completely remove the metastasis. Chemotherapy can promote the radical cure of the entire disease and increase the cure rate. 20% to 40% of patients abroad can be cured through various treatments.

If neoadjuvant chemotherapy cannot achieve tumor necrosis, delaying surgical treatment will affect the survival rate. Because when chemotherapy is ineffective, the tumor will continue to reproduce and microscopic lesions in the lungs will develop. When chemotherapy is effective, delaying radical surgery for the tumor will not jeopardize the survival rate. Preoperative chemotherapy can increase the success rate of limb salvage, so preoperative chemotherapy is safe and beneficial for patients preparing for limb salvage. The effect of preoperative chemotherapy can predict the cure rate. The successful implementation of chemotherapy has enabled osteosarcoma patients to not only improve their survival rate, but also retain their limbs and have a certain degree of joint function.