Laryngeal cancer needs to be differentiated from the following 4 diseases

The clinical manifestations of laryngeal cancer vary according to the location of the cancer. Therefore, patients with hoarseness, throat discomfort, and foreign body sensation should pay attention to differential diagnosis from the following diseases:

1. Laryngeal amyloidosis

Patients present with mild hoarseness and sometimes wheezing-like dyspnea. The lesions often occur in the anterior part of the subglottic larynx, but may also occur in the ventricular zone and vocal cords, presenting as single or multiple nodules, or diffuse thickening of the mucosa. The vocal cords are rarely fixed, the course of the disease is long, and the condition is sensitive to corticosteroids.

2. Benign mixed tumor of larynx

This disease often occurs in the aryepiglottic folds or supraglottic area. The surface mucosa is smooth, the boundaries are clear, and the tumor is solid. The lateral neck X-ray shows a shadow of a mass with smooth boundaries. Pathological examination is of great significance for diagnosis.

3. Benign laryngeal granular cell tumor

The disease is common in young and middle-aged people aged 30 to 40. The lesions are located in the vocal cords, and most patients have hoarseness. The nodules on the smooth mucosa are less than 1 cm in diameter, with unclear boundaries and unrestricted vocal cord movement. Pathological examination is required for diagnosis.

4. Laryngeal plasmacytoma

This disease is common in middle-aged and elderly men and can occur in various parts of the larynx, mostly the epiglottis, vocal cords, ventricular cords and laryngeal ventricles. Patients have symptoms of hoarseness and dyspnea. Laryngoscopy shows diffuse submucosal tumor tissue infiltration in the larynx. The lesions often extend beyond the larynx and involve the pharynx. Pathological biopsy is of differential significance.