What are the pathogenesis of ovarian tumors

So far, the cause of ovarian malignancy is still not very clear. In fact, the occurrence of ovarian malignancy is a complex process with multiple factors and steps, and many risk factors play a role successively or to varying degrees. According to a large amount of statistical data, the following factors may be involved:

(1) Living environment and race The incidence of ovarian malignant tumors varies from country to country. The highest incidence is in Northern Europe and North America, while the incidence in my country is relatively low. The incidence in urban women is higher than that in rural women, and the incidence in women with good economic conditions is higher than that in women with poor economic conditions. In terms of race, the incidence in white people is higher than that in other colored people.

(2) Endocrine disorders Ovarian tumors are more common in single, infertile, or fertile women. The incidence of ovarian cancer increases in women with delayed menarche and premature menopause. Severe premenstrual tension, dysmenorrhea, repeated miscarriages, unusual breast swelling, a history of breast cancer, or a history of endometriosis also increase the incidence of ovarian cancer. These endocrine disorders.

(3) Ovulation frequency and number of ovulations. Ovarian ovulation is a negative stimulus to the stroma on the surface of the ovary. Repeated damage and repair may be a high-risk factor for ovarian cancer. According to statistics from Peking Union Medical College Hospital, the incidence of ovarian cancer is likely to increase with increasing ovulation frequency. Full-term delivery, prolonged breastfeeding, and oral contraceptives can reduce the incidence of ovarian cancer because they reduce the number of ovulations.

(4) Genetic factors: About 20% of patients with ovarian malignancies have a family history. There are three hereditary ovarian cancer syndromes, mainly epithelial, which can put some women at extremely high risk of the disease. Women with no family history of ovarian cancer have a lifetime risk of 1/70. If one first-degree relative is ill, the risk increases to 5%; if two first-degree relatives are ill, the risk is 7%; if there is a first-degree relative with hereditary ovarian cancer syndrome, the risk is as high as 50%, and the risk increases with age.

The above is a detailed introduction by oncologists. We should not lose confidence in the treatment of cancer and other diseases, and we must pay attention to health maintenance. At the same time, some high-risk subjects, such as single, infertile, with a personal history of breast cancer, colon cancer or endometrial cancer, and a family history of ovarian cancer, should be considered high-risk subjects and should be alerted early.