Will endometrial cancer surgery affect female fertility?

Endometrial cancer is one of the three most common gynecological malignancies in women. Its incidence rate ranks first among gynecological malignancies in developed countries and second only to cervical cancer in my country. In recent years, the incidence of endometrial cancer has shown a trend of getting younger. So will endometrial cancer surgery affect women's fertility?

After years of clinical exploration and practice, in 1961, the world reported for the first time that high-efficiency progestins were successfully used in the treatment of endometrial cancer to preserve fertility, bringing a glimmer of hope to endometrial cancer patients of childbearing age who have not given birth.

However, not all endometrial cancer patients who have not conceived during their childbearing years can retain their fertility. Only those who meet the following conditions can initially retain their fertility: ① Young patients ≤ 40 years old who are eager to retain their fertility;

② Pathologically confirmed stage IA, well-differentiated, type I endometrial adenocarcinoma with positive estrogen and progesterone receptors;

③Ultrasound and MRI examinations exclude myometrial infiltration, lymph node and distant metastasis, and ovarian tumors;

④ Normal serum marker CA125 level (<35IU/ml);

⑤Exclude systemic diseases such as abnormal cardiopulmonary function, acute liver and kidney function damage, and coagulation dysfunction

⑥ Exclude patients with a family history of hereditary non-polyposis colorectal cancer, a history of other tumors, or combined tumors in other parts of the body;

⑦ Follow-up can be guaranteed.

Patients who do not meet the above conditions should follow the doctor's advice and be treated according to the treatment principles of endometrial cancer.