Is there a relationship between HPV and uterine cancer

Is there a relationship between HPV and uterine cancer

HPV is not a disease, but a virus called human papillomavirus. Cervical cancer is a disease and the most common gynecological malignancy. It mostly occurs in women aged 30 to 55, but in recent years, there is a trend of younger onset. The disease has no obvious symptoms and signs in the early stage, which is an important reason for people to miss the best treatment period. Many patients are not diagnosed with the disease until the obvious symptoms appear in the late stage. So is there a relationship between HPV and uterine cancer?

Generally speaking, the most common types of HPV infection in the reproductive tract are types 6, 11, 16, and 18. Among them, HPV types 6 and 11 often infect the vulva, anus, vagina and other parts, and are low-risk types. They are more common in women with condyloma or low-grade cervical intraepithelial lesions, but have no obvious association with uterine cancer.
A large number of studies have shown that different types of HPV DNA can be detected in 95% of cervical cancer specimens. The content of HPV DNA detection is positively correlated with the degree of cervical lesions. There is a temporal relationship between HPV infection and cervical cancer, which is consistent with biological phenomena. HPV is closely related to cervical cancer, and other factors may play a synergistic role.
If a woman has more than two male partners, her chance of developing uterine cancer increases significantly. Sexually transmitted disease infection usually indicates a more complicated sexual life, and the chance of developing uterine cancer is relatively higher. If there is long-term damage, skin breakage, erosion, and inflammation of the cervix, it may turn into early uterine cancer cells.

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