What is the reason for the sharp increase in the incidence of colorectal cancer?

Colorectal cancer is one of the common malignant tumors in humans. The incidence rate is high in middle-aged and elderly people, and is more common in men than in women. If colorectal cancer patients have no metastasis, the 5-year survival rate after surgery can exceed 90%; if there is metastasis, the 5-year survival rate after surgery is less than 50%. So what is the reason for the sharp increase in the incidence of colorectal cancer? Let's take a closer look at this issue.

1. Long-term holding back of urine and feces:

Holding back urine and feces is one of the causes of colorectal cancer. Urine contains one or more carcinogens, which can stimulate the bladder epithelium and cause it to become cancerous. Feces contains more harmful substances, such as hydrogen sulfide, skatole, cholesterol metabolites, and secondary bile acid, which can also cause colorectal cancer if they frequently stimulate the intestinal mucosa.

2. Colorectal adenoma cancer:

Chronic inflammation of the colon is a major cause of colorectal cancer. For example, granulomas caused by chronic ulcerative colitis and chronic schistosomiasis are directly related to the occurrence of colorectal cancer. The longer the course of the disease, the higher the possibility of colorectal cancer. The incidence of colorectal cancer in patients with ulcerative colitis for more than 20 years is about 20% to 40%.

3. Dietary factors:

A high-fat, high-meat, low-fiber diet is closely related to the occurrence of colorectal cancer. A high-fat diet not only stimulates increased bile secretion, but also promotes the growth of certain anaerobic bacteria in the intestine. Once cholesterol and bile salts are decomposed by anaerobic bacteria to form unsaturated cholesterol, such as deoxycholic acid and lithocholic acid, both increase in the intestine. The latter two are carcinogens or co-carcinogens, and can therefore lead to the occurrence of colorectal cancer.

The above are the reasons for the sharp increase in the incidence of colorectal cancer. Many patients are not diagnosed until the colorectal cancer is in the middle or late stages. At this time, if the cancer cells have spread, it will be very difficult to cure. Even if all possible treatment methods are used, the average patient can only live for 18 to 20 months. For cancer patients, giving them hope is a treatment method that has both scientific and artistic significance. To achieve this, it is required to improve the nurse-patient relationship, enhance the patient's trust in medical workers, and generate hope in the face of treatment, which is also an important condition for alleviating pain. To gain the trust of patients, you must have a high degree of sympathy and responsibility, warmly care for and respect patients, patiently listen to patients' confessions, and carefully explain. But you need to keep consistent with the doctor's opinion to avoid causing doubts in patients. When explaining to patients, be careful not to talk too much at one time, and gradually make the patient truly understand the problem in time, which can make the patient understand the condition, treatment and prognosis, trust the medical staff, and actively cooperate with the treatment.