What is the normal 24-hour urine protein content?

The so-called 24-hour urine protein quantification, also known as the 24-hour urine protein excretion rate, specifically collects a person's entire urine for 24 hours and conducts detailed testing of the urine protein content in the urine. This is a scientific method to understand whether a person has urine protein. For those with hypertension or diabetes, it is very necessary to do a 24-hour urine protein quantification test. So, what test result is considered normal?

What is the normal 24-hour urine protein level?

Proteinuria actually means that the protein content in urine exceeds the normal value, thus indicating an abnormal disease state. Many people actually don’t know what proteinuria is, nor do they know when proteinuria is considered abnormal. This requires a numerical value to define proteinuria. So what is the normal value of 24-hour urine protein quantification?

What is the 24-hour urine protein quantity?

The normal value of 24-hour urine protein is less than 150 mg/24 hours.

24-hour urine protein measurement is a reliable indicator for determining whether there is kidney disease:

1. Clinically, whether kidney disease occurs or not is usually determined by comprehensive judgment based on the qualitative and quantitative indicators of urine protein in routine urine tests. The qualitative indicator of urine protein is commonly referred to as whether urine protein is negative or positive. If the urine protein test result is positive, the severity of kidney disease is reflected by the number of +'s. The quantitative determination of urine protein can more accurately reflect the kidney function of the subject, and the commonly used diagnostic indicator is the 24-hour urine protein quantification.

2. For normal people, the quantitative range of 24-hour urine protein in routine urine test is less than 150 mg/24 hours. If the quantitative index of 24-hour urine protein of the subject is higher than this normal reference range, it can be considered that there is renal damage.

Although 24-hour urine protein quantification is a reliable indicator for determining whether kidney disease has occurred, it is inaccurate to determine that the subject has kidney disease based on an abnormal result of a single 24-hour urine protein quantification test.

How is proteinuria defined?

Proteinuria, as the name suggests, means that there is protein in the urine, but normal urine also contains protein. Only when the protein content in the urine exceeds the normal value is it clinically defined as proteinuria. Qualitative examination shows urine protein (+) or above; quantitative examination shows urine protein >150mg/d, and greater than 3.5g/d is considered massive proteinuria.

Proteinuria is clinically divided into three types:

How is proteinuria defined? Clinically, it is divided into three situations: 1. Pseudoproteinuria: If blood, pus or vaginal secretions are mixed in the urine, it can cause positive urine protein;

How is proteinuria defined? Clinically, it is divided into three situations: 2. Selective proteinuria: The lesion only damages the charge barrier of the glomerular filtration membrane, reducing the amount of negative charge, then only the filtration of albumin increases, and the protein molecules in the urine are small and medium-molecule proteins.

How is proteinuria defined? Clinically, it is divided into three situations: 3. Non-selective proteinuria: Some glomerular diseases can damage the filtration membrane barrier, such as abnormal enlargement or rupture of the filtration membrane pores, that is, the mechanical barrier is damaged, then the large, medium and small molecular weight proteins in the blood are filtered out without any selection.

This article introduces the definition of proteinuria in detail, as well as the 24-hour quantitative proteinuria. As a person who feels unwell, if you suspect that you have proteinuria, it is best to check it out in time to see if the protein in your urine is normal, so that you can get better treatment.