Special treatment for relieving colorectal cancer pain

The main pain of patients with advanced colorectal cancer is cancer pain. The severe and unbearable pain not only disturbs the patient's mood, but also is not conducive to controlling the disease. Some patients cannot relieve the pain even with strong analgesics. At this time, other special analgesic methods can be adopted.

1. Neurodestructive therapy

The pain relief rate of the three-step drug analgesia is very high, but some colorectal cancer patients are not satisfied with the pain relief effect and have to consider other methods of controlling cancer pain. Neurodestructive blockade is an effective nerve damage treatment method for treating intractable cancer pain. For patients who are ineffective with drug analgesia, or who cannot eat, have drug contraindications, or cannot tolerate analgesics, pain can be relieved by cutting the nerves.

2. Peripheral nerve block

Cancer pain is localized, and when drug treatment is ineffective, using different concentrations of phenol, ethanol, doxorubicin and mitomycin solutions to block peripheral nerves, or using radiofrequency to damage nerves can achieve satisfactory results. Nerve blocks must be located proximal to the stimulus, and commonly used nerve blocks include the maxillary nerve, mandibular nerve, auriculotemporal nerve, greater occipital nerve, suprascapular nerve, femoral nerve, obturator nerve, sciatic nerve and peroneal nerve.

3. Epidural neurodestructive block

Epidural block is a method of injecting neurodestructive drugs into the epidural space to block spinal nerve conduction and produce segmental analgesia. It can block both somatic and autonomic nerves at the same time, with a wide range of blockade; it can avoid irritation of the meninges and damage to the spinal cord or spinal nerves. This therapy does not directly contact the nerve roots, but works outside the dura mater, so the possibility of rectal sphincter involvement is low and the safety factor is high.