What are the diagnostic criteria for kidney cancer

With the development of a large number of basic and clinical studies, a deeper understanding of renal cell carcinoma (RCC) has been enhanced. In 2004, WHO made a new classification of renal cell carcinoma histopathology based on the latest research progress in RCC tissue morphology, immunophenotype, genetic characteristics, and epidemiological characteristics, clinical and imaging conditions, somatic cell genetics, prognosis and other related information. So what are the diagnostic criteria for renal cancer?

Papillary renal cell carcinoma is also known as chromophilic RCC. Its age of onset, male-female incidence ratio, symptoms and signs are similar to those of clear cell renal cell carcinoma. It is common in patients with long-term hemodialysis and acquired renal cystic disease. It is generally believed that papillary renal cell carcinoma has no special imaging features, but in our clinical work, we have found that it appears as an ischemic tumor on enhanced CT scans, and the tumor enhancement is not as obvious as that of typical clear cell carcinoma.
Multilocular cystic renal cell carcinoma is rare. The tumor tissue has clear boundaries, and the cystic cavities vary in size and are filled with serous or bloody fluid. The maximum diameter of the tumor can reach more than 10 cm, and it may even be composed entirely of cystic cavities. Microscopically, the tumor is multilocular cystic, with the cyst wall lined with transparent cancer cells, and aggregated transparent cancer cells are also seen in the intervals of the cysts. Multilocular cystic renal cell carcinoma develops slowly and has a good prognosis.