Neoadjuvant chemotherapy refers to a radiotherapy method of systemic chemotherapy applied before local surgery or radiotherapy of malignant tumors. The advantages of neoadjuvant chemotherapy for breast cancer are that the efficacy is more intuitive, the local treatment effect is improved, the tumor development is curbed, the conditions for breast-conserving surgery are created, and an experimental model is provided. 1. The therapeutic effect is more intuitive Neoadjuvant chemotherapy can observe changes in tumor size, pathological and biological indicators before and after chemotherapy, and intuitively understand whether chemotherapy drugs are sensitive and effective, providing a reliable basis for formulating efficient chemotherapy plans. 2. Improve local treatment effect Neoadjuvant chemotherapy not only makes surgical resection easier, but also makes unresectable tumors resectable, significantly improving the therapeutic effect on the local tumor. 3. Curbing tumor development Angiogenesis inhibitory factors can be produced in malignant tumors, which can inhibit the development of tumors to a certain extent. Neoadjuvant chemotherapy can prevent the acceleration of tumor development and metastasis due to the reduction of angiogenesis inhibitory factors. 4. Create conditions for breast-conserving surgery For patients with large breast cancer tumors, the tumor is significantly reduced after neoadjuvant chemotherapy, and the clinical stage is lowered, so there is no need for a total mastectomy, which creates conditions for breast-conserving surgery. 5. Provide test models Neoadjuvant chemotherapy also provides a good experimental model for studying the relationship between chemotherapy drug sensitivity and certain related biological factors, which is undoubtedly of great significance for achieving individualized treatment. |
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