9 common types of lymphoma

Lymphoma originates from lymph nodes and lymphatic tissues. Its occurrence is often related to the malignant transformation of certain immune cells produced by lymphocyte proliferation and differentiation during the immune response. It is more common in young and middle-aged people aged 20 to 40, and more common in men than in women. In recent years, its incidence has been increasing, which may be related to environmental deterioration, longer life expectancy and progress in histopathological diagnosis. There are 9 common subtypes of lymphoma in clinical practice:

1. Marginal zone lymphoma refers to lymphoma originating from B cells between marginal zone lymph follicles and follicular mantles. It can be divided into lymph node marginal zone B cell lymphoma, splenic marginal zone cell lymphoma and extranodal marginal zone B cell lymphoma of mucosa-associated lymphoid tissue.

2. Follicular lymphoma is a lymphoma that occurs in the germinal center. It is derived from B cells and responds well to chemotherapy, but it is prone to recurrence and becoming invasive.

3. Mantle cell lymphoma originates from B cells in the mantle of follicles. It is more common in elderly men, develops rapidly, has poor chemotherapy response, and the average survival time is 2 to 3 years.

4. Diffuse large B-cell lymphoma is the most common type, which is difficult to treat and has a 5-year survival rate of only 25%.

5. Burkitt's lymphoma is highly malignant and invasive, often occurring in children, and is characterized by involvement of the jaw.

6. Angioimmunoblastic T-cell lymphoma is a type of aggressive T-cell lymphoma and is often treated with chemotherapy containing doxorubicin.

7. Anaplastic large cell lymphoma originates from T cells and progresses rapidly, often accompanied by skin invasion, with or without lesions in lymph nodes and other extranodal sites.

8. Peripheral T-cell lymphoma is an aggressive T-cell lymphoma that often affects the skin, lungs, and central nervous system. Most patients have immune deficiencies, and chemotherapy is ineffective, with a poor prognosis and a survival period of less than one year.

9. Mycosis fungoides is an indolent lymphoma, and the proliferating cells are mature helper T cells.