What is the cancer index CA-125

A female patient underwent a vaginal B-ultrasound examination and was found to have chocolate cysts and endometriosis on her ovaries. The cancer index CA-125 showed 65.5. Can it be determined to be ovarian cancer?

The normal value of the cancer index is 0-35. Consider the possibility of precancerous lesions. If there is a cyst, it will also cause an increase. It is recommended to go to the hospital for examination, such as CT, pathology and puncture biopsy, to see if there are cancer cells. At present, patients should pay attention to rest, avoid excessive fatigue, and eat more nutritious food.

What is the cancer index CA-125?

The cancer index CA-125, or cancer antigen 125, is the preferred marker for ovarian cancer and endometrial cancer. If 65U/ml is used as the positive limit, the accuracy rate of stage III-IV cancer can reach 100%.

CA-125 is the most important indicator for early diagnosis, efficacy observation, prognosis, and monitoring of recurrence and metastasis of ovarian cancer. The combination of CA-125 determination and pelvic examination can improve the specificity of the test.

Dynamic observation of serum CA-125 concentration is helpful for the prognosis evaluation and treatment control of ovarian cancer. After treatment, CA-125 content can decrease significantly. If it cannot return to the normal range, the possibility of residual tumor should be considered. 95% of patients with residual tumor have serum CA-125 concentration greater than 35U/ml. When ovarian cancer recurs, CA-125 can be elevated several months before clinical diagnosis. The serum CA-125 of patients with ovarian cancer metastasis is significantly higher than the normal reference value.

Elevated CA-125 can also be seen in ascites caused by various malignant tumors. Elevated CA-125 can also be seen in a variety of benign gynecological diseases, such as ovarian cysts, endometriosis, cervicitis and uterine fibroids, gastrointestinal cancer, cirrhosis, hepatitis, etc.