Experts explain possible causes of bladder cancer

The cause of bladder cancer is relatively complex. It is not caused by a single factor, but may be the result of multiple factors. We need to pay special attention to the factors related to the cause of bladder cancer. What are the common causes of bladder cancer ? Let's talk about the common causes of bladder cancer.

Common causes of bladder cancer include:

The onset of bladder cancer is a multi-factor, multi-gene, and multi-step process. The accumulation of abnormal genotypes and the effects of the external environment ultimately lead to the appearance of a malignant phenotype. The most widely accepted view on the etiology of bladder cancer is that viruses or certain chemical carcinogens act on the human body, activating proto-oncogenes into oncogenes and inactivating tumor suppressor genes, leading to cancer. More than 80% of bladder cancers are related to carcinogenic risk factors.

Smoking and occupational exposure to aromatic amines are currently clear risk factors for bladder cancer and are also common causes of bladder cancer. Smokers are 2 to 4 times more likely to develop bladder cancer than non-smokers, and the risk is related to the amount of smoking, duration, and degree of inhalation. About half of bladder cancers in Western countries are related to smoking. The specific carcinogens in tobacco that can cause bladder cancer have not yet been identified. Studies have shown that nitrosamines, 2-naphthylamine, and p-aminobiphenyl in smoke increase the metabolites of tryptophan in smokers' urine. Certain occupations, such as workers engaged in the production of aromatic amines, dyes, rubber, aluminum, and leather, painters, and those who frequently use dyes can increase the risk of bladder cancer. One of the main reasons is exposure to aromatic amine substances such as 2-naphthylamine and benzidine. These may all be causes of bladder cancer.

The above is an explanation of the common causes of bladder cancer. I hope it will be helpful to everyone. If you have any questions, you can contact our online experts, who will give detailed answers based on the patient's specific situation.