Experts analyze the main causes of bladder cancer for everyone

According to the statistics of authoritative medical institutions, the incidence of bladder cancer is relatively high worldwide, and the incidence rate of male friends is slightly higher than that of female friends, making many people suffer from bladder cancer. What are the main causes of bladder cancer ? Let's ask experts to tell you about the main causes of bladder cancer.

In general, the main causes of bladder cancer are:

1. Smoking

It is the main cause of bladder cancer. Recent studies have shown that smokers increase the metabolism of the carcinogenic substance tryptophan in their urine by 50%. When smoking stops, tryptophan levels return to normal.

2. Workers who are exposed to aromatic substances for a long time

It is also a major cause of bladder cancer. Workers working in industries such as dyes, leather, rubber, and paint may have a high incidence of bladder tumors.

3. Abnormal tryptophan metabolism in the body

Abnormal metabolism of tryptophan can produce some metabolites, such as 3-hydroxy-2-aminoacetophenone and 3-hydroxy-o-aminobenzoic acid, which can directly affect the synthesis of RNA and DNA in cells. These metabolites are excreted into the bladder through the liver and are carcinogenic after being acted on by β-glucuronidase, which is also a cause of bladder cancer.

4. Long-term local irritation of the bladder mucosa

Chronic local irritation of the bladder wall, such as chronic infection, bladder stones and urinary tract obstruction, may be the cause of bladder cancer. Cystitis glandularis and leukoplakia are considered to be precancerous lesions that can induce cancer.

The above is an analysis of the main causes of bladder cancer. I hope it will help you understand bladder cancer. For more questions about the causes of bladder cancer, you can consult our online experts, who will answer them very seriously.