What are the causes of pancreatic cancer?

Pancreatic cancer is one of the common digestive tract malignancies, and its incidence is quite high. Abdominal pain and painless jaundice are common symptoms of pancreatic head cancer. So what are the causes of pancreatic cancer? The following is a detailed answer from relevant experts.

Cause of pancreatic cancer: drinking

The incidence of pancreatic cancer after drinking varies among different races. According to a study on the relationship between drinking and the incidence of pancreatic cancer in black and white Americans, black male heavy drinkers and female moderate drinkers have a higher incidence rate than white people.

Cause 2 of pancreatic cancer: diabetes

Experimental studies have shown that insulin can promote the growth of pancreatic cancer cells in vitro or in vivo; high concentrations of insulin can activate the insulin-like growth factor-1 receptor, producing growth-promoting effects including changes in cell cycle progression. This is one of the causes of pancreatic cancer.

Pancreatic cancer causes three: smoking

A large number of studies support the close connection between pancreatic cancer and smoking. Possible mechanisms of smoking causing pancreatic cancer: ① Smoking promotes the secretion of tobacco-specific N-nitrite, a carcinogen, into the bile duct, which then flows back into the pancreatic duct; ② The specific effect of tobacco-specific N-nitrite on organs can flow into the pancreas with the blood; ③ Smoking increases blood lipid levels and promotes pancreatic cancer. Smokers may be prone to cancer due to low cell methylation levels. Relevant experiments have confirmed that maintaining adequate folic acid and pyridoxal concentrations can reduce the risk of pancreatic cancer related to smoking.

The above is an introduction to the causes of pancreatic cancer. I believe everyone should have a certain understanding of pancreatic cancer. If you want to know more about pancreatic cancer, please consult online experts.

For more information, please visit the pancreatic cancer disease special topic at http://www..com.cn/zhongliu/yxa/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.