Tumor experts analyze the common causes of gallbladder cancer

The incidence of gallbladder cancer has always been high in my country, and it ranks first among malignant tumors of the gallbladder. Therefore, understanding the causes of gallbladder cancer is of great help in treatment and prevention. The following experts will introduce to us in detail the causes of gallbladder cancer.

What factors are the causes of gallbladder cancer? The following are some common causes of gallbladder cancer :

1. Chronic cholecystitis: Chronic cholecystitis is related to gallbladder cancer. Gallstones, chronic cholecystitis, and gallbladder cancer often coexist. Gallbladder mucosa can evolve into carcinoma in situ through metaplasia, hyperplasia, or polypoid changes. Studies have shown that the progression time from atypical hyperplasia of the gallbladder to advanced cancer is about 15 years.

2. Gallbladder stones: Gallbladder cancer is closely related to gallbladder stones. In Europe and the United States, 54.3% to 100% of patients with gallbladder cancer have gallbladder stones, while in China, the rate is 20% to 82.6%. From the perspective of gallstones, 1.5% to 6.3% of patients with cholelithiasis have gallbladder cancer.

3. Pancreatic-biliary junction malformation: Pancreatic-biliary junction malformation, that is, pancreatic-biliary duct confluence is a congenital digestive system malformation. The most reasonable explanation for the mechanism of pancreatic duct confluence causing gallbladder cancer is the reflux of pancreatic juice.

4. Gallbladder adenomyosis: Gallbladder adenomyosis is a proliferative disease, which is also common in the risk factors that can cause gallbladder cancer. It is mainly characterized by hyperplasia of the gallbladder mucosa and muscle layer, forming intramural diverticula, cysts, etc.

5. Gallbladder adenoma: Gallbladder adenoma is divided into papillary adenoma, tubular adenoma, and tubulopapillary adenoma. Gallbladder adenoma is often pedunculated and solitary, and is now recognized as a precancerous lesion of the gallbladder.

The above are the causes of gallbladder cancer. I believe that through the introduction of experts, you have a certain understanding of the causes of gallbladder cancer. If you have any questions about the causes of gallbladder cancer, please consult our online experts.

For more information, please visit the gallbladder cancer disease special topic at http://www..com.cn/zhongliu/dna/ or consult an expert for free. The expert will then give a detailed answer based on the patient's specific situation.