Diagnostic methods for metastatic bone tumors

Diagnostic methods for metastatic bone tumors

The diagnosis of bone tumors, especially metastatic bone tumors, is very important, complex and difficult. Delayed or wrong diagnosis is very harmful, affecting the recovery and even causing irreversible consequences.

The diagnosis of metastatic bone tumors is generally based on clinical manifestations and X-ray examinations. However, due to the many changes in clinical and X-ray manifestations, misdiagnosis is easy to occur based on one-sided examinations. Although pathological examinations are decisive, the large variation in tissue morphology at different stages of tumor development and the limitations of specimen collection also affect the diagnosis, so a diagnosis cannot be made based on a single item.

Therefore, the diagnosis of metastatic bone tumors follows the principle of three-in-one diagnosis, that is, considering clinical, X-ray and pathological examinations at the same time, and comprehensive analysis is still correct and important, so as to improve the diagnosis rate. However, with the progress and advancement of science and technology, the improvement and increase of diagnostic methods should be changed to a combination of multiple aspects, including clinical manifestations (medical history, symptoms, signs), laboratory tests (routine tests, biochemistry), imaging examinations (X-rays, CT, MRI), pathological examinations and other special examinations (B-ultrasound, radionuclide, immunology, infrared, fluorescence...), combined with each other, comprehensive analysis, further comprehensive diagnosis, differentiation of benign and malignant and differentiation with similar diseases.

The diagnostic methods for metastatic bone tumors are multifaceted, including clinical, laboratory, radiological, pathological and other disciplines, which require comprehensive consideration and comprehensive analysis in order to avoid misdiagnosis as much as possible and facilitate treatment.

Benign bone tumors have clear and sharp boundaries of bone destruction, most of which are surrounded by a sclerotic ring, and the lesions are clearly demarcated from normal bones, such as endosteotic osteochondroma, bone cysts, etc. A few benign bone tumors have a small amount of neat periosteal reaction. After fracture, the periosteal reaction is still neat and clear. There is no Codma triangle. Most benign bone tumors have no soft tissue mass protruding outside the tibia. A few benign bone tumors with obvious expansion have clear boundaries similar to soft tissue masses due to thin cortex.

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