What are the causes of rectal cancer

Rectal cancer is a common malignant tumor in the gastrointestinal tract, ranking third in the global cancer rankings, second only to gastric cancer and esophageal cancer in incidence. The cause of its occurrence is still unclear. In the world of medicine, clinical experts generally believe that the cause of rectal cancer is related to the following factors:

1. Genetic factors : In the families of patients with rectal cancer, many have a family history of cancer, and there are also many digestive tract tumors. Due to the change of genes in normal cells, cancer patients inherit a susceptibility, coupled with certain stimulating factors, which makes tissue cells grow rapidly and develop into cancer. Cell genetic genes mutate and become malignant cells with genetic characteristics, which manifests as a family history of cancer;

2. Dietary factors : The so-called Western diet, which is high in fat, protein and low in fiber, is believed to be related to the occurrence of rectal cancer. Western countries are high-incidence areas for colorectal cancer, and the incidence of rectal cancer is high. In contrast, the Banti tribe in South Africa consumes rough food that is low in fat and rich in fiber, and the incidence of rectal cancer is low. If these residents immigrate to areas with a high incidence of rectal cancer, the dietary structure will change, and the incidence will increase accordingly. This is because high-fat and high-protein foods can increase the amount of methylcholanthrene in the feces, which can cause increased bile acid secretion and be decomposed into unsaturated polyunsaturated hydrocarbons by anaerobic bacteria in the intestines. Both of these substances are carcinogens. The reduction in the amount of fiber slows down the speed at which feces passes through the intestines, which increases the contact time between these carcinogens and the intestinal conjunctiva, leading to an increased chance of cancer.

3. Adenoma canceration : Tubular polyps can become cancerous. Adenomas can be divided into three types: tubular adenomas, villous adenomas, and mixed adenomas. Tubular adenomas have a high incidence rate, and villous adenomas have a high canceration rate. Among adenomas, there are hereditary familial adenomas, which are considered precancerous lesions. They usually occur after the age of 30, but some may become cancerous before the age of 20.

4. Inflammatory bowel disease, ulcerative colitis and Crohn's disease, etc., are caused by the destruction of intestinal mucosa, the proliferation of ulcer repair, and the formation of granulation tissue, which leads to cancer. Schistosoma japonicum eggs are deposited in the rectal mucosa, and chronic inflammation stimulates cancer.

5. Others : such as immune deficiency, genetic factors, viral infection, effects after gastrectomy and cholecystectomy, etc.

The above is what experts tell us about the causes of rectal cancer. I believe everyone has a certain understanding of it. Experts suggest: If you have symptoms of disease in your health, you can choose the appropriate treatment according to your symptoms. Do not delay diagnosis. You should go to a regular hospital in time to avoid delaying the disease. If you have other questions, please consult our online experts or call for consultation. Believe in miracles and wish you health, happiness and joy!

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